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Clinic focuses on Parkinson's research
Tuesday, April 3, 2001
By Tom Corwin Staff Writer

For Jeana Bartlett, the new clinic at Medical College of Georgia
Hospital is a place to address all of the ways Parkinson's disease
affects her life and the life of her caregiver and husband, Richard.

For doctors and researchers at MCG, it is a chance to share
information across disciplines and give patients access to
cutting-edge treatment.

That could mean everything from deciphering how toxins such
as pesticides might be causing Parkinson's or offering patients
the latest in experimental drugs that might prevent the disease.

The MCG Movement Disorders Clinic, scheduled to open in May,
is one of 62 centers of excellence worldwide that are recognized
by the National Parkinson's Foundation.

On Monday, the foundation's chairman of the board, Nathan Slewitt,
came to view the clinic. The foundation provides some funding for
the clinic, such as helping pay a portion of nurse clinician Joan
Carpenter's salary.

``You'll play a powerful role in finding the cause and cure for
Parkinson's,'' Mr. Slewitt told clinicians and patients Monday.

Getting the designation from the foundation, and the prominent
recognition of physicians in the Department of Neurology, was
part of the reason MCG Health Inc. chose to make neurosciences
its first center of excellence, said Don Snell, president and chief
executive of MCG Health.

The designation and the backing from administration has allowed
MCG to expand what it can  offer in basic research and clinical
research trials, said the clinic director, Kapil D. Sethi, a neurologist
at MCG.

The clinic ``treats patients as whole unit, patients and their
caregivers,'' Dr. Sethi said. ``These are very exciting times.''

Although MCG has always been involved in later-stage drug
trials, the clinic is now involved in earlier drug trials that could
offer an earlier chance at a promising therapy, Dr. Sethi said.
For instance, two of the study drugs target proteins involved
in the cell death of neurons, potentially protecting and preserving
them, Dr. Sethi said.

``The next big step is going to be slowing down the disease,''
Dr. Sethi said.

Others, such as neurotoxicologist Debra Gearhart at MCG, are
looking at toxins as a potential cause of the disease. A contaminant
of illegal drugs called MPTP attracted the attention of researchers
because it caused symptoms similar to Parkinson's in its users, Dr.
Gearhart said. The compound becomes something called MPP-plus
in the brain and might lead to increased oxidative stress to the
neurons, leading to damage or death, Dr. Gearhart said. She would
like to test Parkinson's patients for levels of the toxin in their blood,
and the clinic gives her a chance to do that, she said.

For Mrs. Bartlett, it is a place to get assessed by Dr. Sethi,  and also
physical and occupational therapy.

``I'm very excited,'' she said.

For more information on studies at the MCG Movement Disorders
Clinic, or for information on area support groups, call (706) 721-9445.

The CSRA Parkinson's Support Group meets the fourth Tuesday of
every month at 6 p.m. at St. John Towers, 724 Greene St. The Aiken
area group meets the third Tuesday of the month at 7 p.m. at Aiken
Area Council on Aging, 159 Morgan St. N.W.

Reach Tom Corwin at (706) 823-3213.

http://augustachronicle.com/stories/040301/tec_071-6109.000.shtml

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