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Published Saturday, April 7, 2001, in the Akron Beacon Journal.

Genetics wars forming up
Practical implications are as frightening as wide-eyed possibilities are
promising
BY TRACY WHEELER  Beacon Journal medical writer

Lori Andrews has peeked into the future of human genetics. And what
she sees is equal parts frightening and funny.

There will be a time, said Andrews -- a professor at the Chicago-Kent
College of Law and author of The Clone Age -- when our genetic
makeup becomes common knowledge, open to marketers who might
want to fill our mailboxes with junk mail on diets and devices.

Or a time when governments will force prenatal genetic testing, hoping
to encourage women to abort rather than cause taxpayers and insurers
to foot the bill for a sick child.

Or a time when a prenatal genetic test can reveal that a child will be
colorblind. And when he turns 18, he will sue his parents because this
disability, which his parents could have prevented, has kept him from
being an artist. (Andrews calls this a ``wrongful life'' suit.)

She offered such predictions at yesterday's ``2001: The Human Genome
Odyssey Conference: The Science, Business, Law & Ethics of
Engineering Human Life'' sponsored by the University of Akron.

Andrews didn't stop there, though.

Imagine that parents, hoping to avoid a ``wrongful life'' suit, create 12
embryos before pregnancy, testing each embryo's genetic makeup and
choosing the best of the bunch. You decide on one, a boy. Except when
you give birth to a girl, you figure out that the lab screwed up. So you
decide to sue the lab. For what, though? Inferior product? Lost wages,
since women earn less over their lifetimes than men?

Or, maybe, before you can get to that point, you and your spouse can't
decide on which features to choose -- blue eyes or brown, short or tall,
blond or brunette. Torn, you divorce. But then what happens to those
12 embryos? Who has custody?

``More and more, children are being turned into commercial products,''
Andrews told the crowd of about 700 doctors, teachers and students.
``Having a baby is becoming like buying a car. You have to decide on
what features you want.''

A recent poll found that 42 percent of parents said they would choose
to make their children smarter and 43 percent said they would enhance
them physically.

``Should a parent be able to buy their child a height gene?'' Andrews
asked her audience. ``Is that cheating? Or is it just like signing them up
for tennis lessons?''

All this is not hyperbole, she said.

A California court recently ruled that a girl born with Tay-Sachs disease -
- a genetic disorder found in Ashkenazi Jews -- could sue her parents.
And a South Carolina court recently forced a woman to undergo genetic
testing for Huntington's Disease at the behest of her ex-husband who
argued that he should get custody of their child because he'll live longer.

Various speakers at the conference, which runs through today at the
John S. Knight Center, made it clear that current ideas of life and law are
becoming obsolete.

One basic question becomes: What is genetic medicine? Is it just curing
disease? Or is it allowing genetic enhancements to height or memory or
any other personal quality?

There's no easy answer, said Eric Juengst, a professor at Case Western
Reserve University.

Consider Prozac in the same context, he said. Should happiness come
through drugs? Or should it come through self-discipline and
introspection?

If these social questions are difficult to answer, they're simple compared
to the scientific questions.

In discussing stem cell research, which relies on cells taken from
embryos, the very questions of life come into play.

Stem cell research has been shown to heal spinal cord injuries, cure
diabetes, reverse the effects of multiple sclerosis and restore function to
paralyzed limbs in mice and rats. But the morality of such advances have
to be weighed against the question of whether an embryo -- the basic
beginning of human life -- should be sacrificed in labs to heal others.
Ronald M. Green, a professor at Dartmouth College, argued that such
considerations lead to only one conclusion: That the healing powers to
the living is much greater than the possibility that an embryo could
become a human.

At the point when stem cells are removed, he said, the embryo is in very
early development when it's still possible for the embryo to divide into
twins. And 80 percent of the time, he added, embryos at this stage never
implant in the uterus, meaning they would not grow and develop further.

``The beginning of human life is much more complex than the life-begins-
at-conception concept takes into account,'' he said. ``Eggs are not
chickens. Acorns are not oak trees.''

Tracy Wheeler can be reached at 330-996-3721 or
[log in to unmask]

http://www.ohio.com/bj/news/docs/030028.htm

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