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Further Thoughts (April 2001): Although the "cause" of levodopa-induced dyskinesia is well confirmed, precisely why it happens remains a mystery, subject to intense research. The (probably oversimplified) popular ex- planation is that LID results from overstimulation, either acute or chronic, of dopamine receptors. From that statement, a PD patient or caregiver may derive whatever he or she needs to know, in order to select drugs and dosage to meet conflicting requirements of symptom relief, quality of life, and rate of future deterioration. If however this doesn't satisfy your intellectual gluttony, the remainder of this long piece is going to generous hardworking listfriend and webstress Janetp, for inclusion in the website she kindly maintains for me: http://www.geocities.com/joebruman/index.html Cheers, Joe -- J. R. Bruman (818) 789-3694 3527 Cody Road Sherman Oaks, CA 91403-5013 ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn