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Rev Neurol 2000 Nov 16-30;31(10):936-43
[Article in Spanish]
Pineda DA, Buritica O, Sanchez JL, Uribe CS, Arana A.
Grupo de Neurociencias de Antioquia, Linea de Trastornos del Movimiento,
Servicio de Neurologia, Facultad de Medicina Universidad de Antioquia, Medellin,
Colombia. [log in to unmask]
INTRODUCTION: The definition of parkinsonian syndromes is based on clinical
criteria. OBJECTIVE: To determine the frequency and management of parkinsonism,
using criteria of inclusion and exclusion. PATIENTS AND METHODS: We
selected 302
consecutive patients, 147 females and 155 males, with parkinsonism, age 66.8
(11.4) (range: 13-90), grades of education 7.5 (4.3) (range: 0-20). A structured
and quantitative protocol was applied to the sample. RESULTS: The most frequent
parkinsonian syndrome was the defined idiopathic Parkinson's disease with 132
participants (43.7%). Probably idiopathic Parkinson's disease was found in 60
cases (19.9%), and possible idiopathic Parkinson's disease in eight cases
(2.6%); early onset Parkinson's disease in 10 cases (3.3%), juvenile Parkinson's
disease in one case (0.3%), familial Parkinson's disease in five cases (1.7%);
cortical Lewy body disease in 16 cases (5.4%), progressive supranuclear
palsy in
nine cases (3.3%), multiple systemic atrophy in eight cases (2.6%). Secondary
Parkinson's disease was distributed as follow: vascular disease in 24 cases
(8%), local lesion in 11 cases (3%), medications in 16 cases (5.3%),
meningoencephalitis in one case (0.3%) and syphilis in one case (0.3%). Without
medication was found 1.5% of sample, which was in Hoehn & Yarh's state I to II.
In monotherapy was found 23.2%, with two medications 46.7%, with three
23.5% and
with four drugs 5.1%. Levodopa was prescript to 70.9%, anticholinergic to 51.3%,
MAO-B-I to 33.4%, amantadine to 33.1%, D2 stimulants to 18.5%, and COMT-I to
2.6%. CONCLUSION: Structured protocol for assessment of parkinsonian syndromes
allows reliable diagnoses for clinical and epidemiological purposes.
PMID: 11244687 [PubMed - indexed for MEDLINE]
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Ray Strand
Prairie Sky Design
-----------------( on the Edge of the Prairie Abyss )---------------
when the sky is clear
the ground is visible
49/dx PD 2 yrs/40? onset/retired
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