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Iinclude a 1997 short absract . This very much applies to myself and was ,on
reflection, my earliest "warning" when my right leg started to drag after
the occasional cigarette. How common, or otherwise, is this?


Transient worsening of Parkinson's disease after cigarette smoking.
Nishimura H, Tachibana H, Okuda B, Sugita M
Intern Med 1997 Sep 36:651-3
[Related MEDLINE Records]

Abstract
We report a patient with probable Parkinson's disease who experienced a
temporary worsening of his symptoms and signs after cigarette smoking.
Deterioration of tremor, rigidity, and writing disturbance began soon after
the inhalation of cigarette smoke and persisted for 15 minutes. Chewing
nicotine gum also induced a brief worsening of the patient's symptoms.
Aggravation of parkinsonian symptoms after cigarette smoking appeared to be
caused by nicotine alone, although the mechanism for this effect remains
unclear.

Dick Pearce

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