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>The answer is that Comtan inhibits an enzyme in the brain, not the >digestive system. The enzyme breaks down the dopamine after it is >released into the synaptic cleft between neurons. Comtan inhibits this >enzyme and effectively extends the effect of the available dopamine. The data I have says Comtan acts more a peripheric level, liver, plasma and digestive tube. Tasmar is fairly similar but has also a central action. Selegiline passes the blood-brain barrier. Maryse ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn