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>Subject: Treatment for Dementia in PD (AAN 2001) >Date: Fri, 18 May 2001 11:00:38 -0500 > >1. P02.105 Donepezil treatment in Parkinson's disease with dementia: A >double-blind, placebo- controlled crossover study >D Aarsland, JP Larsen, C Janvin, K Laake > >Fourteen patients with PD (mean age 78) with mean Mini Mental Status Exam >score of 20.7 received placebo or donepezil (up to 10 mg/day) for 10 >weeks, followed by crossover to the other arm. Two treated patients >dropped out due to dizziness, nausea, and diarrhea. Mean MMSE score >increased in treated patients by 2.1 points, vs. 0.3 points for placebo >(p=0.02). No change in UPDRS motor scores was seen. > >Sponsored by Pfizer > >2. P02.106 The effect of treatment with rivastigmin (Exelon) on cognitive >functions of patients with dementia and Parkinson's disease >N Giladi, H Shabtai, B Benbunan, T Gurevich, M Anca, S Sidis, AD Korczyn > >Twenty-six patients with PD (mean age 75.8 years) with mean Mini Mental >Status Exam score of 20.7 received open-label rivastigmin up to 6 mg/day >for 26 weeks. Eight patients withdrew, including five for reasons possibly >related to treatment. Increased tremor and salivation occurred in >approximately half of patients. Score on the cognitive subscale of the >Alzheimer Disease Assessment Scale improved by 7.5 points (p<0.05). >Improvement was also seen in the UPDRS mentation score (p<0.03). > >Copyright 2000 WE MOVE >http://www.wemove.org janet paterson: an akinetic rigid subtype, albeit perky, parky . pd: 54/41/37 cd: 54/44/43 tel: 613 256 8340 email: [log in to unmask] . a new voice: the nnnewsletter: http://groups.yahoo.com/group/janet313/ . a new voice: the bbbook: http://www.geocities.com/janet313/wordbook/ . a new voice: the wwweb site: http://www.geocities.com/janet313/ . ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn