 |
 |
> Subject: chronic levodopa use toxic? > From: janet paterson <[log in to unmask]> > Date: Wed, 11 Jul 2001 08:04:52 -0400 hi all as far as i have learned, dyskinesias and dystonias associated with pd and levodopa (sinemet) longterm, are connected to overmedication of levodopa as the disease progresses and the response to meds has to be fine tuned to a greater degree in other words, as my neurologist put it, the 'window' for good symptomatic response beteween undermedicated 'poverty of movement' and overmedicated dyskinesia and dystonia (maybe one could coin the term a 'surfeit of movement') gets narrower and narrower i think the real 'blame' here lies with pd and its degenerative aspect not the meds that is the greatest problem we face at the moment in re long term management of pd in my humble opinion i like to think of it as fine tuning an aging maserati (i wish!) a sledgehammer approach does not work we cannot simply throw more meds at pd to make the symptoms go away janet thirteen/sixteen years and still truckin janet paterson: an akinetic rigid subtype, albeit perky, parky . pd: 54/41/37 cd: 54/44/43 tel: 613 256 8340 email: [log in to unmask] . snail mail: 375 Country Street, Apt 301, Almonte, Ontario, Canada, K0A 1A0 . a new voice: the nnnewsletter: http://groups.yahoo.com/group/janet313/ . a new voice: the wwweb site: http://www.geocities.com/janet313/ . ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn