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>    Subject: ARTICLE: New stem cell experiment ignites ethical controversy
>    From: Murray Charters <[log in to unmask]>
>    Date: Wed, 11 Jul 2001 03:48:28 -0700

New stem cell experiment ignites ethical controversy
BY AARON ZITNER  Los Angeles Times

WASHINGTON -- Inflaming the already heated debate over
stem cell research, a team of Virginia fertility researchers will
report today that they created human embryos for the specific
purpose of disassembling them to obtain the valuable stem
cells inside.

The experiment, which was legal and used no federal funds,
throws a spotlight on one of the murkiest areas of medical
research -- the creation of human embryos for laboratory
experiments -- at an unusually sensitive moment. Within
weeks, President Bush is expected to announce whether
the federal government will fund medical research using
embryo stem cells, capping three years of contentious
debate.

Several experts said the report, from researchers at the
Jones Institute for Reproductive Medicine in Norfolk, Va.,
appeared to be the first published account of scientists
producing embryos for the sole purpose of harvesting
their stem cells.

They said different teams had probably created embryos
for other research purposes, but the practice is not widely
discussed because of possible public backlash. The report
appears in the July issue of the journal Fertility and Sterility.

Embryonic stem cells can grow into any type of cell in the
body, and scientists hope to guide the cells to become
replacement tissue for patients -- new pancreas cells for
diabetics, heart muscle for cardiac patients and brain cells
for Parkinson's patients. But anti-abortion groups say the
research is equivalent to murder because human embryos
are destroyed in the process of obtaining stem cells.

To date, scientists have obtained stem cells from embryos
donated by fertility patients. More embryos than needed
are often produced in the course of treatment. The
government is also eyeing these "spare" fertility clinic
embryos as a source of stem cells should Bush approve
a funding plan. In lobbying the Bush administration,
many scientists and research advocates have argued
that it is more ethical to use these embryos in research
than to have them discarded or frozen indefinitely,
as patients usually decide to do. They have noted that
under National Institutes of Health rules, no embryos
would be created for the federally funded research.

The Jones Institute researchers say they solicited eggs
and sperm from paid donors and used them to create
110 fertilized eggs. Forty matured to the stage where
stem cells usually develop, though the scientists
successfully isolated and cultured cells from only
three of them.

While the researchers said their method had several
ethical and scientific advantages, people on both sides
of the stem cell debate criticized it.

"This is really ghoulish," said Douglas Johnson,
legislative director of the National Right to Life Committee,
an anti-abortion group.

If Bush approves federal funding for research with "spare"
embryos, Johnson said, then scientists, in time, will demand
funding to create embryos for research.

Some supporters of embryo cell research criticized the report
as well, saying that it was clear from work with fertility clinic
embryos that stem cells could be obtained from embryos
created for research purposes.

Alexander Capron, a professor of law and medicine at the
University of Southern California, said: "It suggests that
the scientists themselves don't see a reason to abstain from
something that seems of marginal medical utility, and which
is much more problematic ethically, and is therefore certain
to inflame people" who oppose embryo cell research.

Others said the new report showed that Bush should
support federal funding, because it would bring much
embryo research under federal ethics and public disclosure
rules.

SOURCE: PioneerPlanet / St. Paul (Minnesota)
http://www.pioneerplanet.com/health/hea_docs/82943.htm

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