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Frist Backs Stem Cell Funding
Senate's Only Doctor Supports Research
By Rick Weiss and Amy Goldstein
Washington Post Staff Writers
Thursday, July 19, 2001; Page A01

The campaign for federal funding of human embryo cell research
gained new political momentum yesterday with an announcement
by Sen. Bill Frist (R-Tenn.) that he would back the use of taxpayer
dollars in the controversial but promising field.

As the Senate's only physician, Frist has been a trusted
and influential adviser on medical issues to President Bush,
who is struggling to decide whether to fund research
on embryonic stem cells. Suspense had been building
in recent days as rumors spread that the heart surgeon
was close to taking a position on the research, which scientists
say could lead to treatments for many chronic diseases
but which depends on the destruction of human embryos.

After grappling with the issue scientifically, ethically and morally,
I conclude that both embryonic and adult stem cell research
should be federally funded within a carefully regulated,
fully transparent framework," Frist told a Senate subcommittee
yesterday.

Frist joins a growing list of conservative senators,
most notably Sen. Orrin G. Hatch (R-Utah), who have recently
come out in favor of funding the research -- an issue that has
become an unanticipated test for Bush as he seeks to define
"compassionate conservatism." Sen. Tom Harkin (D-Iowa),
chairman of the Appropriations subcommittee on labor, health
and human services, said yesterday he believes there may
now be as many as 75 votes in that chamber in support
of such funding, enough to overcome a Bush veto.
Other observers said the number may be closer to 65.
They said a majority of House members may now favor the work
as well.

But the battle for Bush's heart and mind is by no means over,
opponents of the research said. Saying the research is too
morally treacherous to justify federal support,
several witnesses yesterday told the subcommittee
that federal funding should be limited to alternative
approaches -- including research limited to adult stem cells.
Some scientists say adult stem cells are less promising.

"The central question to this debate remains: Is the young
human a life or mere property to be discarded as a master
chooses?" said Sen. Sam Brownback (R-Kan.). "Destructive
embryo research -- research which requires the destruction
of living embryos -- is deeply immoral, illegal and unnecessary."

Even Frist warned that his support was contingent on the
implementation of adequate ethics principles, 10 of which
he presented yesterday morning. At least two of those
principles go beyond anything found in the detailed set
of stem cell research guidelines developed last year
by the National Institutes of Health (NIH), raising questions
as to whether funding might be delayed under a Frist regime
until the NIH revises its guidelines.

One of Frist's principles calls for restrictions on the number
of embryo cell colonies, or lines, to be created with federal
money, and suggests a preliminary limit of five years
of funding. Another calls for the creation of an independent
presidential advisory committee to keep tabs
of the research -- a suggestion that some observers
decried as redundant given the large amount of planning
and oversight already provided by NIH and the presidentially
appointed National Bioethics Advisory Commission.

In an interview yesterday, Frist said he believed those
differences could be worked out. "My object is not to slow
things down," he said.

He and several other supporters of embryonic stem cell research
said they did not support a bill co-sponsored by Harkin
and Sen. Arlen Specter (R-Pa.), which would allow federal
funds to be used not only for research on embryo cells
but also for the direct destruction of embryos to get those
cells -- activities not allowed under the current
NIH guidelines.

Frist and other supporters of the research also spoke out
yesterday against the creation of human embryos solely
for the purpose of harvesting their stem cells. That practice
was endorsed at yesterday's hearings by representatives
of the Jones Institute for Reproductive Medicine in Norfolk,
which last week reported it was doing just that,
and by Michael West, president of Advanced Cell Technology
in Worcester, Mass., who has said his company hopes
to clone human embryos as a source of stem cells.

Frist's announcement came on the same day that the NIH
officially released a 200-page report that concludes that
more research is needed on both embryonic and adult stem
cells to determine their relative promise.

Frist has spoken to the White House in the past about the
question of stem cell research. But he and other sources
yesterday said that he did not develop his position
in consultation with the administration.

In contrast with legislation to protect patients in HMOs,
which Frist and two other senators drafted this year deliberately
to be in sync with Bush's stance on that issue, "this was
something he did on his own," one administration official said.

The White House said that Frist's views would not necessarily
carry more influence with the president than those
of other members of Congress. "The president will make
his own decision after looking at all the scientific, ethical
and legal issues involved," said deputy White House press
secretary Scott McClellan.

But other Congress watchers said they suspected Frist's views
would indeed have disproportionate impact, and could be
especially crucial if Bush decides against funding and Congress
takes up the issue on its own.

"If we end up in Congress, the support of such an influential
senator could be crucial," said Michael Werner, bioethics
counsel for the Biotechnology Industry Organization.

Separately yesterday, Vice President Cheney suggested that
Bush will announce his decision by the end of August.
"He recognizes the enormous significance of the decision
and so he's really dug into it in great depth and talked
to a great many people about it," Cheney said on
"The NewsHour with Jim Lehrer."

Asked by Lehrer whether there was room for compromise
on the issue, Cheney said it was not that simple. "It's not
like highway money. There's no way you can split the
difference -- 'you get your highway and I get my highway.'
These are deeply, deeply significant ethical questions
about the future of the race, about medical research,
about our ability to deal with horrendous diseases,
and at the same time give due regard to the sanctity of human life.
It's appropriate that he should take plenty of time to make sure
he understands all of the ramifications of it, that he's comfortable
with the final course he decides upon."

SOURCE: The Washington Post
http://www.washingtonpost.com/wp-dyn/nation/A16219-2001Jul18.html

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