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In a message dated 7/17/01 4:04:36 PM, [log in to unmask] writes: << not just another dopamine agonist, or else it would not have any neuroprotective effects >> Maybe, yes and maybe, no. See source: http://www.parkinson.org/pramipexole.htm Summary: RESULTS: Pretreatment of the cells daily for 72h with pramipexole [agonist, brand name MIRAPEX] significantly decreased the effects of MPP+ on mitochondrial membrane potential and cell death. The protective action was not observed when pramipexole was added to the cell cultures at frequencies less than every 24th. CONCLUSIONS: These results suggest that daily treatment with pramipexole maintains mitochondrial membrane potential and this protects neuronal cells from apoptotic cell death It seems that there's always some entertaining magic to be found in those lab dishes. ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn