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E-MOVE reports from the 14th International Congress on Parkinson's Disease, Helsinki July 28-Aug 1. Poster and Platform session numbers refer to those in the abstract book, published in Parkinsonism and Related Disorders 2001;7(Supplement). The clinical importance of dyskinesia C Clarke Dyskinesias have a significant impact on quality of life and health care costs, according to data presented in a symposium by Dr. Carl Clarke. Three hundred twenty-one patients spanning a range of disease severity were evaluated over six months for dyskinesias via UPDRS part 4a and the Goetz Scale. Other measures used included SF-36 for health parameters, MADRAS for depression, and patient diaries for health care visits and expenditures. Increased dyskinesias were highly significantly correlated with decreased health on SF-36, with the major effect on mental health. Correlation, which was calculated after controlling for motor fluctuations and disease deterioration, was more significant for UPDRS score than for Goetz score. Similar correlation was found for dyskinesias versus MADRAS score, potentially indicating an important role for dyskinesias in aggravating reactive depression. Costs for the most severely dyskinetic patients were doubled compared to patients without dyskinesias, from approximately $3000/year to $6000/year. Clarke suggested these results may provide an economic rationale for treatments that delay onset of dyskinesias. Supported by Glaxo SmithKline. --- Funding for E-MOVE meeting reports is provided in part by unrestricted educational grants from Allergan Inc., Elan Pharmaceuticals, and Pharmacia Corporation. Copyright 2000 WE MOVE Editor: Richard Robinson ([log in to unmask]) This service is provided free of charge to the Internet community, courtesy of WEMOVE.org. This document may be freely redistributed by email only in its unedited form. We encourage you to share it with your colleagues. E-MOVE archives, plus information on subscribing, are available at http://www.wemove.org/emove. To unsubscribe, send an e-mail to [log in to unmask], with "unsubscribe e-move" in the message body. E-MOVE is a service of WE MOVE (Worldwide Education and Awareness for Movement Disorders) 204 West 84th Street New York, NY 10024 TEL 800-437-MOV2 TEL 212-875-8312 FAX 212-875-8389 http://www.wemove.org ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn