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Dear List Friends, I was one of the small % that had some rather serious problems with the use of Ropinerol. Symptoms included "Sleep Attacks" and mini siezures ( I would sieze in mid sentence while talking to someone - while eating, etc. etc.) I landed on the floor many times and even in the ditch with my truck while driving on a nomber of occasions. Ropinerol removed and back on sinemet and the problems went away (in that regard ......). Again be careful what you take and ask lots of questions first -there is a lot on Doctors Guide, Medscape, and PDR which one should be aware of and MAKE YOUR CAREGIVER AWARE OF before embarking down a new path ! Requip may work well for a lot of folks, but caution in all that we do is most advisable, and we must be ever watchful as we are the only ones who really know how we feel. Rob ----- Original Message ----- From: "Linda J Herman" <[log in to unmask]> To: <[log in to unmask]> Sent: Tuesday, August 07, 2001 3:51 AM Subject: Fw: High-Dose Ropinirole (PD Congress 2001) > --------- Forwarded message ---------- > From: WE MOVE <[log in to unmask]> > To: <[log in to unmask]> > Date: Mon, 6 Aug 2001 23:06:26 -0500 > Subject: High-Dose Ropinirole (PD Congress 2001) > Message-ID: <[log in to unmask]> > > E-MOVE reports from the 14th International Congress on Parkinson's > Disease, Helsinki July 28-Aug 1. Poster and Platform session numbers > refer > to those in the abstract book, published in Parkinsonism and Related > Disorders 2001;7(Supplement). > > High-dose ropinirole allows reduction in levodopa and lessening of > dyskinesias in advanced PD patients, according to these two studies. > > 1. Efficacy and tolerability of high dose ropinirole in patients with > Parkinson's disease (PD) and levodopa-induced late motor complications > UF Polzer, H Hundt > P-TU-222 > > Twenty-one patients increased their mean ropinirole dose from 8.2 mg/day > to 29.7 mg/day, and their daily levodopa dose from 770 mg/day to 555 > mg/day (p<0.001), over a period of 8 weeks or less. After 12 weeks, > duration of daily dyskinesia was reduced from 30.4% of the day to 4.6%, > while "off" periods were reduced from 42.6% to 14.6%. Four patients > developed psychotic symptoms. One patient withdrew due to psychosis, and > six others for reasons believed to be unconnected to treatment. > > Supported by SmithKline Beecham > > > 2. High-dose ropinirole in advanced Parkinson's disease > C Pacchetti, F Mancini, R Zangaglia, S Cristina, F Blandini, E Martignoni > P-TU-219 > > Thirty-six patients increased their mean dose of ropinirole from 16 > mg/day > to 35 mg/day, and reduced levodopa from 752 mg/day to 588 mg/day > (p=0.001). Dyskinesias during "on" were reduced 40%, and dystonia during > "off" was reduced by 40%. No treatment-emergent side effects were > reported. > > --- > Funding for E-MOVE meeting reports is provided in part by unrestricted > educational grants from Allergan Inc., Elan Pharmaceuticals, and > Pharmacia > Corporation. > > Copyright 2000 WE MOVE > Editor: Richard Robinson ([log in to unmask]) > > This service is provided free of charge to the Internet community, > courtesy of WEMOVE.org. This document may be freely redistributed by > email only in its unedited form. We encourage you to share it with your > colleagues. > > E-MOVE archives, plus information on subscribing, are > available at http://www.wemove.org/emove. > To unsubscribe, send an e-mail to [log in to unmask], > with "unsubscribe e-move" in the message body. > > E-MOVE is a service of WE MOVE (Worldwide Education and Awareness for > Movement Disorders) > 204 West 84th Street > New York, NY 10024 > > TEL 800-437-MOV2 > TEL 212-875-8312 > FAX 212-875-8389 > http://www.wemove.org > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn