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10 months of Requip, Mirapex and SinemetCR. Nothing, no improvement at all. Neuro has made an appointment for me at a large University research hospital to see a Movement Disorder Specialist. The 3 1/2 hour round trip is horrible to think about, I hate car trips. He thinks I have "striatal nigra degeneration" which he called untreatable Parkinson's. Oh well Mike ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn