Print

Print


Was the "yes" really a "no"?
08/20/2001 04:04 AM
STEM CELLS

AMERICAN government funding is the engine that drives
cutting-edge medical research around the world. President
George W. Bush has opened the door to funding the
potentially revolutionary field of embryonic stem cell
research. But it is becoming increasingly unclear just
how far that door has opened.

Mr. Bush's compromise was a painstaking effort to allow
the research to proceed while adhering to his campaign
pledge that he would not support practices that involve
destroying human life, even at the earliest cellular stages.

Mr. Bush decided to allow funding, now estimated at
$100 million, for research only on the 60 embryonic
stem cell lines already believed to be in existence
around the world, where "the life and death decision
already has been made." Another $150 million will go to
research on stem cells derived from adult human tissue,
which most scientists feel are also promising, but not
capable of developing into as many different kinds
of tissue and treating as many conditions.

Controversy immediately surrounded that number 60.
If there are indeed 60 healthy stem cell lines, and if they
are reasonably available to scientists, they would
comprise an acceptable beginning of American
participation. But the White House is refusing to tell
scientists precisely who owns these colonies, making
it impossible to determine if the cells are available or
viable. Not all stem cell lines are hearty enough to
withstand research techniques and keep reproducing.
Some die for unknown reasons, others become infected.
Scientists feel most comfortable with lines that have
been peer reviewed in scientific journals, now estimated
at between 10 and 20.

Predicting that the 60 cell owners themselves will come
forward soon, the administration says it cannot provide
a list of labs because information on the privately owned
cells is considered proprietary. Officials at the National
Institutes of Health said they hope to compile a registry
of stem cell lines over the next few months. Meanwhile,
the world's top scientists remain in a holding pattern.

"Anything that restricts access to human embryonic
stem cells will inevitably result in delay, and that is not
good for patients who are paralyzed, bed-ridden,
wheelchair-bound or who have diabetes, heart attacks
or strokes," said Dr. Ira Black, a leading stem cell researcher
at the University of Medicine and Dentistry of New Jersey.

If it becomes evident in the next few months that there are
not 60 suitable embryonic stem cell lines available to
American scientists, Mr. Bush's limited "yes" to research
essentially becomes a "no."

Bills that would fund broader research on stem cells derived
from surplus frozen embryos earmarked for destruction in
fertility clinics have been introduced by Republican Sen.
Arlen Specter of Pennsylvania and Democratic Rep.
Jim McDermott, a Washington physician.

Mr. Bush has said he would veto such a bill, but some
people close to him have speculated that he could
change his mind.

Sooner or later, Congress should move to fund the
broader research, if only to allow it to proceed at full force.

If Mr. Bush's 60 promised cell lines do not materialize,
it is all the more reason for Congress to act now, passing
the measure with enough support to override a veto.

SOURCE: The St. Louis Post-Dispatch
http://www.stltoday.com/stltoday/news/stories.nsf/News/Editorial/

* * *

----------------------------------------------------------------------
To sign-off Parkinsn send a message to: mailto:[log in to unmask]
In the body of the message put: signoff parkinsn