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On 11 Aug 2001, at 12:40, Judith Richards posted:

> Placebo Effect Probed in Parkinson's
>  By Adam Marcus - HealthScout News Reporter
>
> THURSDAY, Aug. 9, 2001 (HealthScoutNews) -- Scientists have long
> believed that Parkinson's disease patients seem to be highly
> susceptible to the placebo effect. Now they know more about why.
>
> Sham treatment of people with Parkinson's triggers a flood of the
> same brain messenger molecule that "active" drugs target -- and from
> the same region of the brain that's damaged by the disorder, new
> research says.
>
> "We conclude that dopamine release in the nigrostriatal system is
> linked to expectation of a reward -- in this case the anticipation
> of therapeutic benefit," write the authors, led by Raul de la
> Fuente-Fernandez, a visiting scientist at the University of British
> Columbia's Neurodegenerative Disorders Center.


If this is true, then I wonder how much the expectation of a reward,
not only as symptomatic relief from taking meds, but also from any
non-PD-related reward source, affects symptoms in our daily lives and
is a factor in what we perceive to be the effects of our regular meds?

Phil Tompkins
Amherst, Massachusetts
age 63/dx 1990

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