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Lionel -- I really have no specific advice, just my sympathy and caring wishes. You both have been going thru hell and I empathize. Hope everything turns out as well as it can. Ann Gibbons -----Original Message----- From: Lionel Modra <[log in to unmask]> To: [log in to unmask] <[log in to unmask]> Date: Friday, August 24, 2001 6:37 AM Subject: Epidural for PWP ??? >My wife, who is the PWP in this family, is scheduled for surgery >(Proctectomy, Sigmoid Colostomy. Cystectomy, Urostomy) on Sept 5, and we >were advised yesterday that the usual procedure is to insert an epidural >catheter (prior to surgery) to introduce pain relieving medication post >operatively. >Does anyone know if there are any undesirable side effects of this >procedure in PWPs? >We are aware of the Pethidine / Selegiline reaction, and have ensured >that all involved in her treatment are also aware of that interaction. >She fell and fractured her 3rd sacral vertebra, damaging the S3 nerves, >in Feb '99. The nerve damage resulted in dysfunction of both bladder >and bowel (retention), and continuous pain in the pelvic area, >increasing in intensity as the bladder and rectum fill. No improvement >in the nerve function has occurred, hence the move to surgical >intervention. She has tried all the available medications, and nerve >stimulation (Medtronic), but unfortunately without success. Life for her >revolves around self-catheterisation and enemas at present. >The stress of this problem has accelerated her PD (she has gone from >good control with 450 mg levodopa per day, to on/off control with 1,100 >to 1,200 mg per day. She also takes 2 x 5 mg Selegiline / day. She has >not been able to take any of the agonists because of their constipating >effect, and the effect of reducing blood pressure. >We would appreciate any comments or advise regarding the epidural, or >other PD related matters. >Lionel Modra, c/g for Win (71\67\??) > >---------------------------------------------------------------------- >To sign-off Parkinsn send a message to: mailto:[log in to unmask] >In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn