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It is with fair frequency that PWP suffer from confusion, memory loss, delusions and hallucinations after surgery. This in part has been attributed to the sedatives and analgesics received around the time of surgery. More often than not, they are also removed from familiar surroundings into hospital and rehab facilities, that makes the problem surface as well. A mild dementia is often in the background Very often these problems subside on their own within a few days, which I realize has not been the case with your uncle. Under those circumstances, with the help of a neurologist, the antiparkinsonian medications (particularly Sinemet or dopamine agonists, can be scaled down slightly (by 20 to 50% as appropriate) temporarily, and the situation may improve. As an alternative, one could add a tranquilizing antipsychotic drug like Quetiapine (Seroquel) in small doses, or both. Each individual is different, and this has to be done with the approval and guidance of his doctors. Check to make sure whether his antiparkinson medications have not been increased, hoping to mobilize him faster. This is often attempted, and sometimes causes some problems too. If they have been increased, then scaling down somewhat may be beneficial, even if it means that there is slight temporary decrease of antiparkinsonian effect. Once he clears, then the drugs can be gently titrated up again. These changes need to be discussed with his providers, and best, his neurologist. Jorge Romero, MD ----- Original Message ----- From: "Ellen Garvey" <[log in to unmask]> To: <[log in to unmask]> Sent: Monday, August 27, 2001 9:26 AM Subject: Memory loss and delusions ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn