Hi Charlie:
Thanks for putting a human face on PD transplant research.
I saw an abstract somewhere, that used engineered cells
that are sensitive to a rare antibiotic. If the cells
were over productive, they can be trimmed back with
an exposure to the antibiotic.
Puts "re-" back in research.
Ray
.....................................................
"Charles T. Meyer, M.D." wrote:
>
> HI
> Ray, David and list,
>
> I saw you mention my name. And yes I was part of the second fetal
> transplant double blind study . This is the Olanow,Freeman, Goetz group who
> ran the experiment for 2 years and then the experiment did not finish on
> time. I likely will officially know the outcome of that study next month
> but I am relatively sure I got the cells. However in addition to some
> improvements I developed, a runaway dyskinesia . This is what Fahn called
> this movement which developed and This is dyskinesia which is not
> controlled by reducing the l-dopa taken., I then followed up with STN -DBS
> surgery which helped a great amount. The dyskinesia virtually vanished on
> the Left, while on the right I do develop some dystonia even with my
> stimulators off
>
> I have mixed feelings about the continuation of this process. I am hoping
> that the surgery winds up useful to somebody else. I think that placement
> of the cells is an important issue. Also the differences in the patients is
> likely important. I do feel the research should continue at a slow pace
> since I am hoping that stem cells will be a cure(and the use of 8-12 week
> embryos will be a relic of the past), It sounds as though Freed and
Do you have the inside scoop?
Of these fetal implants, is the active ingredient
stem cells in the tissue?
> Fahn had quite a disagreement .Fahn saying that the procedure should not
> be done and Freed giving a more positive read on it, The design of the
> Olanow/Freeman/Goetz is for longer (2 years) which has made waiting for
> the blind to be broken excruciatingly long especially since I was subject
> 002 in 1995 or 96. In spite or maybe because of this study experience I
> still am a strong advocate of research
> and double blind studies using patients.
>
> Thanks for letting me let off a little steam here.
perfect place,
Reality check
Appreciated.
Thanks for the inside scoop to an interesting subject.
> Charlie
>
> 01:18 PM 8/25/01 -0700, you wrote:
> Ray,
>
> Do you ever monitor the PD list (PIENO)? There were a few who had been a
> part of the fetal implant studies. One that I remember for sure is Dr.
> Charles Meyer (psychiatrist) Charlie had some bad dyskinesias because of it.
> I remember another couple who had the "placebo" surgery
>
> Charles T. Meyer, M.D.
> Middleton, WIsconsin
>
Ray Strand
Prairie Sky Design
-----------------( on the Edge of the Prairie Abyss )---------------
when the sky is clear
the ground is visible
49/dx PD 47/40? onset
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