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If you would like a copy of our monthly publication "The Vermont Parkinsonian" News magazine E-Mail us your postal address and we will send you one. A PD maagazine unlike any other. Sid Burton, Editor & Publisher Charles Countryman wrote: > I made the mistake of combining two different things in my message. > However, at least in my case, the same remedy works for both, but for > different reasons. > > I find that deliberate movement, such as walking, will alleviate > dyskinesias. I like the convenience of Sinemet CR, but the release of > medication and its utilization by the body does vary. Sometimes there > is too much and the result is dyskinesia. > > Sometimes there is not enough medication. Deliberate movement is not an > immediate help for that. But I think that the affect of PD on the heart > and circulatory system needs more emphasis. Basically, I think that > sometimes the pump just needs to be primed and deliberate movement > serves that purpose. > > Jorge A Romero MD wrote: > > > > > It is important to separate out the effects of too much treatment from > > insufficient treatment. In general, dyskinesias occur when the dose of > > Sinemet peaks too high; stiffness and rigidity emerge when the level of > > medication drops (trough level) too low to be fully effective. Since > > Sinemet (even CR) is a short acting medication, high peaks and low > troughs > > can occur in the same person. > > > > > > > Jorge A Romero, MD > > > > ----- Original Message ----- > > From: "Charles Countryman" <[log in to unmask]> > > To: <[log in to unmask]> > > Sent: Thursday, August 23, 2001 5:28 PM > > Subject: Re: levodopa side effects...need help > > > > > > > >>Barbara, > >> > >>I try to spread my Sinemet CR out over the day in five hour periods > >>(6am, 11am, 4pm, 9pm). However frequently I wake up in pain and very > >>stiff early in the morning. Taking a 1/2 dose of Sinemet before going > >>back to bed helps me a lot. > >> > >>I have also had problems with Dopamine Agonists (e.g. low blood > >>pressure). It helps me to take Amantadine and reduce the Dopamine > >>Agonists. > >> > >>If I am having problems with dyskinesias or very slow movement, walking > >>around the house and basic T'ai Chi exercises help me get my mind and > >>body together. > >> > >>Have you tried SAM-e (S-adenosylmethionine)? My experience over the > >>past year is that SAM-e seems to extend the effectiveness of my other > >>meds and helps with depression. SAM-e may help my liver process the > >>other meds. I take 400mg of SAM-e in the morning and again in the early > >>afternoon. > >> > >>My re-introduction to this list. I have not been active on the list for > >>a couple of years. I am 50, diagnosed with PD in 1993 after I was > >>misdiagnosed in 1991 with carpal tunnel syndrome in my right arm and old > >>sport injuries in my right leg. My current meds are Selegiline 5mg x 1, > >>Sinemet CR 200-50 x 4, Ropinirole 1MG x 3, & Amantadine 100mg x 2 (with > >>a supplemental 1/2 dose of Sinemet CR if I wake up too early) > >> > >>Charley > >> > > > > ---------------------------------------------------------------------- > > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > > In the body of the message put: signoff parkinsn > > > > > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn