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Our thanks to those who replied.
But, has anyone had this procedure, or do the MD,s on the list have any
comments.

> -----Original Message-----
> From: Parkinson's Information Exchange Network
> [mailto:[log in to unmask]] On Behalf Of Lionel Modra
> Sent: Friday, August 24, 2001 7:53 PM
> To: [log in to unmask]
> Subject: Epidural for PWP ???
>
>
> My wife, who is the PWP in this family, is scheduled for
> surgery (Proctectomy, Sigmoid Colostomy. Cystectomy,
> Urostomy) on Sept 5, and we were advised yesterday that the
> usual procedure is to insert an epidural catheter (prior to
> surgery) to introduce pain relieving medication post
> operatively. Does anyone know if there are any undesirable
> side effects of this procedure in PWPs? We are aware of the
> Pethidine / Selegiline reaction, and have ensured that all
> involved in her treatment are also aware of that interaction.
> She fell and fractured her 3rd sacral vertebra, damaging the
> S3 nerves, in Feb '99. The nerve damage resulted in
> dysfunction  of both bladder and bowel (retention), and
> continuous pain in the pelvic area, increasing in intensity
> as the bladder and rectum fill. No improvement in the nerve
> function has occurred, hence the move to surgical
> intervention. She has tried all the available medications,
> and nerve stimulation (Medtronic), but unfortunately without
> success. Life for her revolves around self-catheterisation
> and enemas at present. The stress of this problem has
> accelerated her PD (she has gone from good control with 450
> mg levodopa per day, to on/off control with 1,100 to 1,200 mg
> per day. She also takes 2 x 5 mg Selegiline / day. She has
> not been able to take any of the agonists because of their
> constipating effect, and the effect of reducing blood
> pressure. We would appreciate any comments or advice
> regarding the epidural, or other PD related matters. Lionel
> Modra, c/g for Win (71\67\??)

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