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Paul, You are right. It is important not to give up on meds. Finding a doctor willing to let you try the different combinations is pretty important when your meds are causing problems. I will say with comtan we almost gave up because it took nearly 10 weeks to find the balance for Nancy. In the beginning all it seemed to to was turn her urine orange. Bob Martone [log in to unmask] http://www.samlink.com/~bmartone -----Original Message----- From: Parkinson's Information Exchange Network [mailto:[log in to unmask]]On Behalf Of P&B Fahr Sent: Monday, September 17, 2001 12:54 PM To: [log in to unmask] Subject: Re: New Member and a Nightmare ----- Original Message ----- From: ROBERT A MARTONE <[log in to unmask]> To: <[log in to unmask]> Sent: Monday, September 17, 2001 11:45 AM Subject: Re: New Member and a Nightmare You Wrote: >3. The COMT inhibitors do work for Nancy and we have found >Comtan to be the best. It has allowed her to reduce sinemet >intake by almost 50%. Bob, Comtan may work the best for Nancy. For other patients all Comtan does is make the urine orange. You have to keep trying them till you find one (if any) that work. Tasmar requires testing but is worth it if you get the needed benefit. As with all PD meds you have to find what works for each individual patient. Paul ---------------------------------------------------- ------------------ To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn