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>> Is there some conflict between vitamin B-6 and some PD meds? >> Ken Rowland Quoting Abe Lieberman: B-6 at 15 mg or less is fine with sinemet. Above this level it may interfere with the effectiveness of sinemet. Quoting Kathrynne Holden: There are some concerns regarding B vitamins for people with PD, though not specifically with deficiency of B6. Long-time users of Sinemet have sometimes been found to have increased levels of serum homocysteine compared to people who have not used Sinemet. Homocysteine is normally cleared from the blood by vitamins B6, B12, and folate, working together. Kuhn W, Roebroek R, Blom H, van Oppenraaij D, Przuntek H, Kretschmer A, Buttner T, Woitalla D, Muller T - Elevated plasma levels of homocysteine in Parkinson's disease.. Eur Neurol 1998 Nov;40(4):225-7. Muller T, Werne B, Fowler B, Kuhn W: Nigral endothelial dysfunction, homocysteine, and Parkinson's disease. Lancet. 1999; 354. Yasui K, Kowa H, Nakaso K, Takeshima T, Nakashima K. Plasma homocysteine and MTHFR C677T genotype in levodopa-treated patients with PD. Neurology 2000 Aug 8;55(3):437-40 ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn