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There is another way of splitting the Sinemet, by dissolving the tablet in orange juice (it must be acid with ascorbic acid (Vit C), so that the dissolved levodopa remains reasonably stable for a few hours). If you dissolve it in 3 oz of OJ, then you can take one ounce at a time to make 1/3 the dose. Jorge Romero, MD ----- Original Message ----- From: "Nina P. Brown" <[log in to unmask]> To: "Jorge A Romero MD" <[log in to unmask]> Sent: Sunday, September 23, 2001 11:36 PM Subject: Re: WHERE TO PURCHASE L--DOPA? Thanks for your reply. I did ask the neurologist and he said people have been able to get it in a few days. Neither my pharmacist, Walgren's or Eckards said that their suppliers could get it for them. I will try #2 tomorrow. I know it will take more l-dopa than Sinement because of the breakdown, but the reason we are trying l-dopa is to titrate the Sinement down. I'm taking 1/2 of a 25/100 every three hours to function and have dyskinesias. We were going to try the l-dopa equivalent of 1/3 of a Sinement because the Sinement would be too difficult to cut properly and later try to increase my mirapex to see if we could ease the dyskinesias. Thanks for your reply. nina Jorge A Romero MD wrote: > I do not know where you can get levodopa, but I have some suggestions: > > 1) Ask the neurologist who prescribed it. > 2) Write or call Dupont or Mylan or Athena, who make the brand name and > generics for products containing levodopa, if it is possible to get the > levodopa alone directly from them. They might be able to give you the name > of a local supplier. > 3) Ask your pharmacist whether, even if it is not in stock, it may be > special ordered. > > It seems to me, however, that the same effect should be possible by reducing > the dose of Sinemet. Using levodopa alone merely decreases the amount that > gets to the brain by allowing the drug to be broken down outside the brain. > One reason that levodopa is not used alone is that such "peripheral" > breakdown is associated with more side effects, such as dizziness and > nausea. > > Jorge A Romero > > ----- Original Message ----- > From: "Nina P. Brown" <[log in to unmask]> > To: <[log in to unmask]> > Sent: Sunday, September 23, 2001 12:05 PM > Subject: WHERE TO PURCHASE L--DOPA? > > > Does anyone know where I can get l-dopa? In an attempt to > > reduce my dyskinesias, my neuro has prescribed l-dopa > > without the carbidopa found in Sinemet. I have called > > numerous pharmacies in Houston, but no one seems to have a > > supplier who stocks it. > > > > Thanks, > > nina > > > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn