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Nilo Sarmiento wrote: > Dear Kathrynne, > First, on B6 over 10 mg caution...doesn't the carbidopa content take care > of that? My understanding of the caution in the literature is that if > levodopa is taken all by itself, then one must observe the restrictions on > the intake of B6 and certain types of food and fruits. Nilo, it's true that when levodopa alone was taken there were warnings to avoid B6 supplements, and also foods rich in B6. And it's also true that when carbidopa was added, it "protected" the Sinemet from the effects of normal amounts of B6. In fact, the literature states that supplements in amounts up to 25 mg of B6 is OK. Personally, I have found that some people are more sensitive to large amounts of B6 than others, so I recommend that supplements greater than 10 mg should be taken separately from the Sinemet. You are in the process of conducting experiments, however; so why not determine for yourself the right amount of B6? You could start with 10 mg and work up and see if there is any difference in the way Sinemet is absorbed, length of time before it takes effect, etc. > My observation has been that over the past six months, the intake of > sinemet did make an appreciable difference in my "feeling of well-being," > the literature calls a "false sense of well-being." However, I did not have > a sense of improvement on my other symptoms (hand tremors, freezing on my > feet, impaired speech). Nilo, has your neurologist commented at all on the extent of your symptoms and any change in them? Sometimes it's harder to notice on oneself than on another person. > I am surprised that you are the only one who has responded to my email, and > I do not know what that means. Well, it could just mean that everyone is spending a lot of time watching CNN, out of concern for the world events today (I know my husband and I have the TV on constantly now) and so they have less time to read and respond to PIEN. But PIEN has weathered many crises and soon people will be respondind, as they normally do. Good luck with your trials of B vitamins and SAM-e, and please do keep the list informed of your results. Best regards, Kathrynne -- Kathrynne Holden, MS, RD "Ask the Parkinson Dietitian" http://www.parkinson.org/ Author: "Eat well, stay well with Parkinson's disease" "Guidelines for Medical Nutrition Therapy for Parkinson's disease" http://www.nutritionucanlivewith.com/ ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn