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NICE DRUG- so wonderful to see FDA and big money working together to protect our health. Glad it was recalled. Rob ----- Original Message ----- From: "ROBERT A MARTONE" <[log in to unmask]> To: <[log in to unmask]> Sent: Tuesday, October 09, 2001 5:24 PM Subject: Baycol Recall and PD question > List, > > One of the members of our PD support group called me tonight > to ask a question about a drug call Baycol that she was > taking for cholesterol reduction. She had a fair amount of > trouble with the drug and it was recalled. After > discontinuance of the drug she began to experience Parkinson > symptoms and has been diagnosed with PD recently. Some info > on Baycol is listed below. I noticed that it may have > produced high concentrations of iron and muscle related > problems. Any body else had any experience with this drug? > Any PD connection? > > ----------------------------------------------------------- > Baycol > > Rhabdomyolysis has been associated with the use of > cholesterol-lowering statins such as Baycol® and Lipobay®. > Rhabdomyolysis is a muscle disorder in which muscle cells > are destroyed and the byproducts released into the > bloodstream. Once in the bloodstream, these byproducts are > carried to the kidneys where the body's filtration system > operates to cleanse the blood. > > Cellular destruction to skeletal muscles generally results > in the release of myoglobin into the bloodstream. Myoglobin, > because it contains iron, can, in excessive concentrations, > occlude or clog the pathways of the kidneys, and lead to > kidney failure and eventual death. Compounding this kidney > distress is an associated shift in the body's vital fluids > from the bloodstream into the muscular system. > Rhabdomyolysis and its severe effects are what reportedly > caused the 31 deaths associated with the use of Baycol® and > Lipobay®. > > Symptoms of rhabdomyolysis include: > > abnormal urine color - usually dark red or brownish; > muscle pain, weakness and/or tenderness; fever; nausea; > vomiting; general malaise. > Muscle pain, weakness or tenderness often occur in the > muscles of the lower back and the calf (leg) muscles. > However, any and all muscle groups can be affected. > > > Bob Martone > [log in to unmask] > http://www.samlink.com/~bmartone > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn