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Neurology 2001 Oct 23;57(8):1497-9

Improved accuracy of clinical diagnosis of Lewy body
Parkinson's disease.

Hughes AJ, Daniel SE, Lees AJ.

United Kingdom Parkinson's Disease Society Brain
Research Centre (Drs. Hughes, Daniel, and Lees),
Institute of Neurology, London, UK.

The authors studied the accuracy of clinical diagnosis
of idiopathic PD (IPD) in 100 consecutive clinically
diagnosed cases that came to neuropathological
examination. Ninety fulfilled pathologic criteria for
IPD. Ten were misdiagnosed: multiple system atrophy
(six), progressive supranuclear palsy (two),
post-encephalitic parkinsonism (one), and vascular
parkinsonism (one). Assessment of the clinical
features suggests that an accuracy of 90% may be the
highest that can be expected using current diagnostic
criteria.

PMID: 11673599 [PubMed - in process]

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