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I was in the trial in 1998-1999 for six months, but not for "off."  This drug is
much like selegiline, Eldepryl.

Charlotte Mancuso

Linda J Herman wrote:

> I received the following message from CenterWatch about clinical trials
> in many locations for rasagiline. SEE summary of the study below and the
> forwarded message. Is anyone already participating in a  trial of this
> drug?
> Linda
>
> "Trial Information
>
> Summary: PRESTO (Parkinson's Rasagiline: Efficacy & Safety in the
> Treatment of "OFF")
> The Parkinson Study Group (PSG), in collaboration with Teva
> Neurosciences, Inc., is conducting a study for patients with moderate to
> advanced Parkinson's Disease. This 26-week study will examine the safety,
> effectiveness and tolerability of an investigational drug in patients who
> do not experience full benefit from their L-dopa dosage.
>
> The study plans to recruit 450 subjects at 59 sites across the United
> States and Canada. Enrollment began in September 2000. For more details,
> contact one of the participating sites near you."
> <http://www.centerwatch.com/patient/studies/stu30215.html>
>
> --------- Forwarded message ----------
> From: CenterWatch Patient Notification Service <[log in to unmask]>
> Date: Sat Nov  3 06:42:19 2001
>
> New clinical trials recently posted on the CenterWatch web site at
> http://www.centerwatch.com.
>
> 1) PRESTO (Parkinson's Rasagiline:  Efficacy & Safety in the Treatment of
> "OFF"). This study is being conducted in:
>     - Toledo, OH
> (http://www.centerwatch.com/patient/studies/stu30219.html)
>     - St. Louis, MO
> (http://www.centerwatch.com/patient/studies/stu30204.html)
>     - Tampa, FL
> (http://www.centerwatch.com/patient/studies/stu30191.html)
>     - Temple, TX
> (http://www.centerwatch.com/patient/studies/stu30223.html)
>     - Rochester, NY
> (http://www.centerwatch.com/patient/studies/stu30215.html)
>     - San Francisco, CA
> (http://www.centerwatch.com/patient/studies/stu30177.html)
>     - Southfield, MI
> (http://www.centerwatch.com/patient/studies/stu30202.html)
>     - Philadelphia, PA
> (http://www.centerwatch.com/patient/studies/stu30220.html)
>     - Phoenix, AZ
> (http://www.centerwatch.com/patient/studies/stu30171.html)
>     - Richmond, VA
> (http://www.centerwatch.com/patient/studies/stu30226.html)
>     - Omaha, NE
> (http://www.centerwatch.com/patient/studies/stu30205.html)
>     - Oxnard, CA
> (http://www.centerwatch.com/patient/studies/stu30176.html)
>     - Pawtucket, RI
> (http://www.centerwatch.com/patient/studies/stu30222.html)
>     - New York, NY
> (http://www.centerwatch.com/patient/studies/stu30212.html)
>     - New York, NY
> (http://www.centerwatch.com/patient/studies/stu30213.html)
>     - New York, NY
> (http://www.centerwatch.com/patient/studies/stu30214.html)
>     - New Haven, CT
> (http://www.centerwatch.com/patient/studies/stu30188.html)
>     - New Hyde Park, NY
> (http://www.centerwatch.com/patient/studies/stu30211.html)
>     - New Orleans, LA
> (http://www.centerwatch.com/patient/studies/stu30198.html)
>     - Miami, FL
> (http://www.centerwatch.com/patient/studies/stu30190.html)
>     - Minneapolis, MN
> (http://www.centerwatch.com/patient/studies/stu30203.html)
>     - New Brunswick, NJ
> (http://www.centerwatch.com/patient/studies/stu30206.html)
>     - Little Rock, AR
> (http://www.centerwatch.com/patient/studies/stu30170.html)
>     - Los Angeles, CA
> (http://www.centerwatch.com/patient/studies/stu30175.html)
>     - Manhasset, NY
> (http://www.centerwatch.com/patient/studies/stu30210.html)
>     - Irvine, CA
> (http://www.centerwatch.com/patient/studies/stu30174.html)
>     - Jacksonville, FL
> (http://www.centerwatch.com/patient/studies/stu30189.html)
>     - Kansas City, KS
> (http://www.centerwatch.com/patient/studies/stu30197.html)
>     - Houston, TX
> (http://www.centerwatch.com/patient/studies/stu30224.html)
>     - Indianapolis, IN
> (http://www.centerwatch.com/patient/studies/stu30196.html)
>     - Iowa City, IA
> (http://www.centerwatch.com/patient/studies/stu30194.html)
>     - Farmington, CT
> (http://www.centerwatch.com/patient/studies/stu30187.html)
>     - Fountain Valley, CA
> (http://www.centerwatch.com/patient/studies/stu30172.html)
>     - Fresno, CA
> (http://www.centerwatch.com/patient/studies/stu30173.html)
>     - Cleveland, OH
> (http://www.centerwatch.com/patient/studies/stu30218.html)
>     - Denver, CO
> (http://www.centerwatch.com/patient/studies/stu30185.html)
>     - Denver, CO
> (http://www.centerwatch.com/patient/studies/stu30186.html)
>     - Chicago, IL
> (http://www.centerwatch.com/patient/studies/stu30195.html)
>     - Cincinnati, OH
> (http://www.centerwatch.com/patient/studies/stu30216.html)
>     - Cleveland, OH
> (http://www.centerwatch.com/patient/studies/stu30217.html)
>     - Boston, MA
> (http://www.centerwatch.com/patient/studies/stu30199.html)
>     - Boston, MA
> (http://www.centerwatch.com/patient/studies/stu30200.html)
>     - Charlottesville, VA
> (http://www.centerwatch.com/patient/studies/stu30225.html)
>     - Augusta, GA
> (http://www.centerwatch.com/patient/studies/stu30193.html)
>     - Baltimore, MD
> (http://www.centerwatch.com/patient/studies/stu30201.html)
>     - Birmingham, AL
> (http://www.centerwatch.com/patient/studies/stu30169.html)
>     - Albany, NY
> (http://www.centerwatch.com/patient/studies/stu30208.html)
>     - Albequerque, NM
> (http://www.centerwatch.com/patient/studies/stu30207.html)
>     - Atlanta, GA
> (http://www.centerwatch.com/patient/studies/stu30192.html)
>
> In addition to the CenterWatch patient notification service, through a
> collaboration with The HealthExchange, patients can also be actively
> matched to select clinical trials.  Visit
> http://www.centerwatch.com/thehealthexchange.html to learn more about the
> HealthExchange Clinical Trials Matching Service.
>
>              ---------------------------------------------------------
>
> CenterWatch offers other publications and services that you can use to
> learn about clinical trials for your medical condition.  We publish a
> series of reports that focus on specific illnesses.  Each report provides
> information about clinical trials results, drugs in development and
> ongoing clinical studies.  Visit
> http://www.centerwatch.com/bookstore/pubs_cons_nmtform.html to see if
> there is a report for you.
>
> ----------------------------------------------------------------------
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