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Hi Lorraine, Just my two cents. I'm amazed that you can see any benefit from such a small dose of Requip. Requip has a high dosing range, and although there is always individual responses to therapy, .25 mg, that is 1/4 mg 3t/day is far less than what I thought was a therapeutic dose, which I believe is 6 to 7 mg per day, or, say, 2 mgs 3 times per day. Is your neuro intending to titrate up your dose? I'm curious to know what benefit you're getting from having added it. For what it's worth I take Requip (3 mg) 4 times a day usually with food, and sinemet before or long after meals, 4 times per day (25/10). It's interesting to see how very different individual responses are. Regards, Charlotte Lorraine Jeffe wrote: > This has been discussed before,but I wasn't taking it at that time.Right > now I'm taking 25/100 of sinement 3 times a day. > Because of a slight balance problem I was put on requip .25 mg 3 times > a day.this summer took them together, but I was having some nausea. My > neuro suggested I take the requip with meals and this seemed to be the > solution. In addition to the nausea I had some dizziness.For the last > two weeks I've tried to take my sinement at least 45 mins. before > meals,which seems to be easy to do before breakfast,but not usually for > lunch and dinner. It was suggested that I take the requip every eight > hrs to maximize the benefit.Well that's o.k. the first thing in the > morniing,but the middle one and the last of the day are done at all > times. I am a snacker and have difficulty eating a lot at meals except > breakfast.My system seems to tolerate the requip without taking at meals > now and I've had only one dizzy spell,which lasted just a few > seconds.Also I'm not certain whether my gait is as good later in the day > then it was.Well I guess my question is just what is the optimum way to > take these two meds--together, spread out, etc? > Perhaps Kathryan could answer this. > > Thanks > > Lorraine Jeffe > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn