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Hi Charlotte, Thanks for answering me.I was prescribed the Requip,because of a balance problem. At first I had some feelings of nausea,but at my neuro's suggestion of taking it with meals solved that.I also experienced some dizziness d just stop and lower my head and that would leave after a few seconds.This was back in MI. and the neuro that I've had some time.He's also chairman of the Michigan Parkinson Foundation of which I'm also on.. Since we now spend about 6 mos, in AZ. II also have a neuro here. He's the one that told me to get maximum benefit I should take Requip about every 8 hrs. and take the sinement a minimum of 30 mins. before meals.It seems my life style has found this difficult to do.Ihave a call in to him now,so we'll see what he says. We are indeed all different!!It sound like your method is working well for you and,of course, that's what really counts. If we could find a cure that would really be fantastic. Best Lorraine Charlotte M wrote: > Hi Lorraine, > > Just my two cents. I'm amazed that you can see any benefit from such a small > dose of Requip. Requip has a high dosing range, and although there is always > individual responses to therapy, .25 mg, that is 1/4 mg 3t/day is far less than > what I thought was a therapeutic dose, which I believe is 6 to 7 mg per day, or, > say, 2 mgs 3 times per day. Is your neuro intending to titrate up your dose? > I'm curious to know what benefit you're getting from having added it. For what > it's worth I take Requip (3 mg) 4 times a day usually with food, and sinemet > before or long after meals, 4 times per day (25/10). It's interesting to see > how very different individual responses are. > > Regards, > > Charlotte > > Lorraine Jeffe wrote: > > > This has been discussed before,but I wasn't taking it at that time.Right > > now I'm taking 25/100 of sinement 3 times a day. > > Because of a slight balance problem I was put on requip .25 mg 3 times > > a day.this summer took them together, but I was having some nausea. My > > neuro suggested I take the requip with meals and this seemed to be the > > solution. In addition to the nausea I had some dizziness.For the last > > two weeks I've tried to take my sinement at least 45 mins. before > > meals,which seems to be easy to do before breakfast,but not usually for > > lunch and dinner. It was suggested that I take the requip every eight > > hrs to maximize the benefit.Well that's o.k. the first thing in the > > morniing,but the middle one and the last of the day are done at all > > times. I am a snacker and have difficulty eating a lot at meals except > > breakfast.My system seems to tolerate the requip without taking at meals > > now and I've had only one dizzy spell,which lasted just a few > > seconds.Also I'm not certain whether my gait is as good later in the day > > then it was.Well I guess my question is just what is the optimum way to > > take these two meds--together, spread out, etc? > > Perhaps Kathryan could answer this. > > > > Thanks > > > > Lorraine Jeffe > > > > ---------------------------------------------------------------------- > > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > > In the body of the message put: signoff parkinsn > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn