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I am 48 years old, female and have had parkinsons fo r 16 years. i was a nurse before the trmors made it difficult to work. i've never posted a messege before so I hope what i'm doing is ok with everyone.I had a hysterectomy done in the spring of this year and noticed that for about 3-4 days post op i required almost none of my daily meds. I felt the best that i've felt for 5 years.I'm taking Sinemet CR 50/200 6x/day, Mirapex 0.5mg 6x/day, Comtan 200mg 6x/day, Norvasc 2.5mg /day and now premarin .625mg /day. This only lasted 3-4 days but when i told my neuro he said it was because I was in bed most of the time. I was out of bed the night of surgery and walking the halls by the next day. i would like to know if anyone else has ever had this happen to them? The second question is does anyone else have alot of off and on with their meds? It doesn't seem to matter if I take them exactly on schedule, I am either very ridgid and full of tremors or have too much and having dyskinesia. My neuro just keeps telling me to keep up with exercise, when i can, and theres hope around the corner for new treatments in the coming years. I'm tired of waiting and think i'm starting to get depressed. Sincerely Kathy Greis Ft. Myers, Florida ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn