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The way of practice in the UK in situations where hallucinations and confusion develop as a side effect of medication is that we slowly withdraw medications starting with anticholinergics, then selegeline, dopamine agonists until the hallucinations settle. We occasionally use atypical neuroleptics to dampen the hallucinations, but theses often have a negative effect on the parkinsonism symptoms. Generally the pros and cons of medication have to be weighed carefully in each individuals case. No two PWP are the same. As other types of medication has been tried, have you tried very slowly reducing the Amantadine to a stage where the side effects are tolerable? What about a long acting drug overnight to help the morning cramps? we use long acting dopamine agonists and controlled release preparations of L-dopa. Discuss this with your clinician. Anna -----Original Message----- From: yesim erman [mailto:[log in to unmask]] Sent: 23 November 2001 04:13 To: [log in to unmask] Subject: Re: Amantadine Dear Anna, The generic names are ; Levadopa + Selegiline + Dopamin antagonist ( Dopergin ) He stopped using Selegiline and Dopergin and started using Amantadine instead. He often had duedenum dyskinesia and he was describing the feeling saying that a belt was squeezing his stomach right under his ribs. This new medication didin't help him much though. It just relieved his morning cramps completely. Yesim "Blockley, Anna" wrote: > Can you tell me the generic names not the trade names - in the UK we have > different trade names - what were the reasons for stopping previous > treatments? > > -----Original Message----- > From: yesim erman [mailto:[log in to unmask]] > Sent: 23 November 2001 02:03 > To: [log in to unmask] > Subject: Re: Amantadine > > Dear Anna, > > He used Madopar + Moverdin + Dopergine for 10 years > Now he has been taking Madopar + Amantadine ( three times a day half a > tablet ) > > "Blockley, Anna" wrote: > > > I am not a doctor and am unable to explain your consultants reasons for > > adding in Amantadine at such a late stage. I would suggest you talk > > thoroughly to both your father and his consultant to weight the benefits > of > > continuing on Amantadine against discontinuing. Is he on 100mg once daily > or > > twice daily? What is his PD drug history? > > > > -----Original Message----- > > From: yesim erman [mailto:[log in to unmask]] > > Sent: 22 November 2001 23:26 > > To: [log in to unmask] > > Subject: Re: Amantadine > > > > Dear Anna, > > He had some dyskinesia problems especially duodenum dykinesia, and in the > > past 2 > > months he fell down at home 3 times. That's why we took him to his doctor > > and he > > decided to add this drug. > > > > "Blockley, Anna" wrote: > > > > > Yes Amantadine does have side effects of hallucinations and or > confusion, > > it > > > is not an uncommon side effect in the elderly or those who have had PD > for > > > 10 years or more. > > > However, research has shown Amantadine may have a soft antidyskinetic > > effect > > > in high doses - why did his Dr prescribe Amantadine? for dyskinesia or > > > general enhanced PD control? > > > Anna > > > > > > -----Original Message----- > > > From: yesim erman [mailto:[log in to unmask]] > > > Sent: 22 November 2001 21:37 > > > To: [log in to unmask] > > > Subject: Amantadine > > > > > > Dear List Friends, > > > > > > I am on the list for my father. He has Parkinsn for 10 years. He used > > > Madopar for 10 years, and 2 weeks ago, his doc. decided to add > > > Amantadine to his drugs. He started taking Amantadine ( Symmetrel ) but > > > he started to see lots of hallucinations and his speech became slurred. > > > Has any of you used this drug and have you ever seen or heard such side > > > effects or more serious ones? We are thinking of dropping this drug. > > > What are your suggestions.. > > > Thank you. > > > Yesim > > > > > > ---------------------------------------------------------------------- > > > To sign-off Parkinsn send a message to: > > mailto:[log in to unmask] > > > In the body of the message put: signoff parkinsn > > > > > > This email and any files transmitted with it are confidential and solely > > for > > > the use of the individual or entity to whom they > > > are addressed. 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