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Hi Leo, Thanks for your response. I had tried increasing my agonist (Miripex) but began having memory problems so had to cut back. May try adding Comtan though. I tried it once before with no apparent relief of symptoms, but may not have given it enough time. Best Regards, Vicky Lynn Leo Fuhr <[log in to unmask]> wrote: Welcome to PIEN. This is a good place to learn from others. We do all react differently to meds. Seems like we often are in a "time to change" with meds. I'm increasing agonist to try to extend and improve how my body uses sinemetCR. Try us out and learn and share. Jeanette Fuhr Vicki wrote about... Subject: New to List from Rosemount, MN 47 have had PD 12 Yrs F ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn --------------------------------- Do You Yahoo!? Check out Yahoo! Shopping and Yahoo! Auctionsfor all of your holiday gifts! ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn