I have been on ultram for over 45 days for pain in my shoulders,back & legs. I was told to take 1 or 2 every 8 hours as needed. Nothing had helped before but ultram was great. It also helps my tremors. I don't take it every day & seldom take it every 8 hours. I doc says it works thru the central nerves system. I am glad to have it. A good evening from Kansas where the weather is great 65 to 70. ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn