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Permax and Parlodel are two others

The agonists all seem to have many adverse side effects.  Ted fell asleep at
the wheel while using Mirapex.  Fortunately, I was in the car.  That was the
end of that.  Started on Requip but drowsiness again a problem.

Carole
PWP Ted (54/46/40)
age now/age diagnosed/age at onset of symptoms

-----Original Message-----
From: Emily and Julian Brinac <[log in to unmask]>
To: [log in to unmask] <[log in to unmask]>
Date: Wednesday, January 23, 2002 11:45 AM
Subject: Re: Read: Re: Driving while on Mirapex or ReQuip in Canada


>What other agonists are there that would not cause withdrawal of driving
>privileges and would be helpfull for PD?
>Emily, Ontario
>----- Original Message -----
>From: "Gail Vass" <[log in to unmask]>
>To: <[log in to unmask]>
>Sent: Wednesday, January 23, 2002 2:04 PM
>Subject: Read: Re: Driving while on Mirapex or ReQuip in Canada
>
>
>> Sleep attacks associated with Parkinson's drugs
>>     CBC CANADIAN NEWS WebPosted Tue Jan 22 16:17:48 2002
>>
>> OTTAWA-- Health Canada has sent out warnings about two drugs used to
>treat
>> Parkinson's disease. They say the drugs can cause sudden sleep
>attacks.
>>
>> Studies dating back to 1999 show links between pramipexole (Mirapex)
>and ropinirole
>> (ReQuip) and sleep attacks.
>>
>> A recent study by the University of Manitoba found 21 out of 420
>patients using the
>> medications reported dozing off at the wheel. The study was supported
>by Boehringer,
>> the manufacturer of Mirapex.
>>
>> The study has been published in the most recent issue of the Journal
>of the American
>> Medical Association.
>>
>> As a result, Health Canada has directed the drugs' manufacturers,
>Boehringer and
>> GlaxoSmithKline, to send letters to physicians to warn patients "not
>to drive or
>> engage in other activities where impaired alertness could put
>themselves and others
>> at risk of serious injury or death."
>>
>> * The letter obliges physicians in most provinces to * inform the
>motor vehicle
>> authorities when they prescribe the drug to a patient.
>>
>> "This is a major problem, because these are the drugs we want to use
>in patients
>> while they're still young with Parkinson's disease," says Dr. Douglas
>Hobson of the
>> University of Manitoba.
>>
>> "These are patients are still functioning and. doing well working, and
>if you
>> suddenly tell them they can't drive, it's a huge issue for them."
>>
>> Provinces have different rules regarding medically unfit drivers.
>>
>> Outright ban on driving inappropriate
>>
>> Doctors have to tell departments of motor vehicles in Manitoba, New
>Brunswick,
>> Newfoundland andLabrador, the Northwest Territories, Nunavut, Ontario,
>Prince Edward
>> Island, Saskatchewan and Yukon, when they prescribe these drugs.
>>
>> Discretionary reporting is the rule in Quebec and Nova Scotia.
>>
>> In Alberta, it is at the discretion of the physician but mandatory for
>the patient
>> to report the change in their medical condition.
>>
>> For British Columbia, there's a blanket prohibition in the province
>for people on
>> these drugs to drive.
>>
>> In Manitoba and Ontario, transportation departments assess each case
>individually
>> before deciding whether to prohibit the person from driving.
>>
>> The study says doctors can assess if their patients are prone to sleep
>attacks by
>> using something called an "Epworth Score."
>>
>> "(It's) a standardized assessment of how sleepy a person would be,"
>says Hobson.
>> "Patients can complete it in the waiting room and then bring it in for
>the physician
>> to reviews."
>>
>> Hobson says an outright ban on driving would be inappropriate. He says
>doctors have
>> enough information now to pick "who is safe to drive and who isn't."
>>
>> The Parkinson's Society is hoping to meet with Health Canada and
>provincial motor
>> vehicle departments to issue new recommendations regarding the drugs
>and driving.
>>
>> The society says people are actually refusing to take the drugs they
>need because
>> they're reluctant to give up their driving privileges.
>>
>> Copyright © 2002 Canadian Broadcasting Corporation - All Rights
>Reserved
>>
>http://cbc.ca/cgi-bin/templates/print.cgi?/news/2002/01/22/Consumers/Par
>kinsonsdrugs_020122
>>
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