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Research to Address Symptoms of Early Parkinson's Disease

ANNAPOLIS, Md., Jan. 28 /PRNewswire/ -- There is no cure
for Parkinson's disease ...  If you or a loved one has had
Parkinson's disease for less than seven years, are 30 years
of age or older, and not using Levodopa, Requip(R), Mirapex(R),
or Permax(R) therapy, you may be interested in finding out more
about a research study for the symptoms of Parkinson's disease.

In the United States, approximately 1.5 million people
are believed to suffer from Parkinson's disease and about
50,000 new cases are reported every year. Because symptoms
usually appear later in life, these figures are expected to grow
as the average age of the population increases over the next
several decades.  Fifteen percent of patients are diagnosed
before age 50, and some physicians have reported more cases
of "early-onset" Parkinson's disease (under the age of 40)
in the past several years. The cause of Parkinson's disease
is unknown but research in this area is active with new
findings being reported.

Parkinson's disease is a progressive neurological disorder,
evidenced by symptoms growing worse over time, that is
a result of loss or degeneration of nerve cells in a region
of the brain that controls movement.  This gradual
degeneration of nerve cells causes a reduction in
a naturally occurring chemical known as dopamine.
Dopamine, a neurotransmitter, is crucial to human
movement. It is the messenger between the nerve cells
that initiates and controls movement and balance.
Symptoms of Parkinson's disease can include tremors,
rigidity or stiffness of the limbs and trunk, slowness
of movement, and impaired balance and coordination.
When symptoms grow severe, the drug Levodopa,
which helps to replace the brain's dopamine, is often
prescribed to treat symptoms of the disease.

Pharmacia is currently seeking males and females for
a research study to evaluate the safety and effectiveness
of an investigational medication that is a dopamine
receptor agonist, for the treatment of early Parkinson's
disease.

Individuals 30 years of age or older, who have had
Parkinson's disease for less than seven years, and do not
have a history of taking Levodopa for a year or more,
may be eligible to participate in this study.  All individuals
who qualify for the study will receive study medication
and study-related health exams. Patients who complete
the study will have the option of continuing in an open
label study. During that time, study medication and
study-related medical care for Parkinson's disease,
will continue to be provided for up to four years or until
the study drug is approved.

Potential study volunteers should call 1-800-41-STUDY
for a preliminary screening.

SOURCE Pharmacia
Web Site: http://www.EarlyParkinsons.com

SOURCE:  PR Newswire
http://www.prnewswire.com/

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