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Debra, my name is Dee. I have been dx'd with PD since Nov. 2001 (just a few months now). I'd had symptoms for around 4 years before I was told it was PD. I've been on Requip for almost 2 months and the first relief I felt was a relaxing of the muscle tightness in my left hand and leg. I have dealt with the fatigue and lethargy that are the side effects of Requip because I have been expecting that it would eventually make me feel good & the tiredness would pass. I have only titrated up to 6 mg a day (2mg/3 times a day) and I'm told that the average maintenance dosage is between 10 & 15 mg a day. So far, I do not feel all that well on Requip. Today I'm having a really bad day as the pain that the Requip at first alleviated seems to be coming back with a vengeance. I'm 58 years old & was hoping to delay beginning Sinement for as long as possible but I'm wondering if I am sacrificing a decent quality of life in doing so. Today was so bad I barely moved around the house...spent most of it in bed in pain. I would like to know if you feel that your decision to quit Requip & begin Sinement has improved your ability to function. The last part of your message to the forum did not appear so I was disappointed to miss your comments. If you could answer my question either via personal e-mail or posted to the forum I would appreciate it. Thanks Dee ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn