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Hi Jim Finn, our current media star, and other less famous "PIEN'ers", Count me in your corner, Jim, in the Great Sinemet Debate. I've been taking it since 1989, every day. It is a wonderful medication for me. I find myself agreeing with Jim wholeheartedly about Sinemet. There is definitely confusion and fear about SInemet . I wonder how many doctors realize that Parkinson's requires dopamine replacement. Sinemet takes care of this, by the breakdown of its L-dopa to dopamine. Mirapex, Requip , Parlodel and Permax all simulate dopamine, but cannot substitute for it. Apples and oranges are not inter- changeable. I like Jim's comparison of avoiding Sinemet to not using the best china in your house.. The other drugs mimic the action of dopamine, but with heavy costs---like knock-down dizziness, low blood pressure and horrible constipation. And a bit of speculation... I would wager that Janet Reno may be a victim of Mirapex. I would bet that she takes too much Mirapex. This would explain why she faints. Ivan Suzman, PWP Portland, Maine 52/39/36 On Sat, 16 Feb 2002 23:06:08 EST [log in to unmask] writes, in part: > Group - > > I am seeing more and more people talking about Sinemet and their > fears about > its use. Here's my 2-cents worth. > > I have had PD for 22 years; diagnosed in 1980 at 32. I'll be 54 > next month. > And I have been on Sinemet since Day 1. So I guess you could say > I've had a > lot of experience with this medication. > > > As PD progresses one of those problems is erratic or unpredictable > performance. It goes with the territory. > But the point is that after 22 years of PD and 22 years on Sinemet, > the > medication is still a useful one. And now, since the operation, I > use less > of it, too. > > Take heart. Going on Sinemet is not the end of life as we know it. > Until > some other kind of therapy comes along it's the best bet. While it > is > probably best to use the minimum amount of it, do not shun its > potential > benefits. > > And use your "good" china, too. > > Regards - > > Jim Finn > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn