Hi, I have been taking selegeline since my original diagnosis, 13 years ago, in conjunction with several other meds, presently these are Madopar, Cabaser, Amantadine and Amitriptyline. It has been my experience that Selegeline helps to "smooth out" the uptake of the Madopar, as well as prolonging the "on-time". The main downside for me from Selegeline is that it caused me to have difficulty getting to sleep at night. My neuro' prescribed Amitriptyline to counteract this, which it does, but this in turn brings its own package of side effects, speech difficulty being the main one. So, as usual, it is a trade off between the side effects and benefits of each combination of meds'. Good Luck. Nigel, age 47, diagnosed at 35. ----- Original Message ----- From: "Debra Sutton" <[log in to unmask]> To: <[log in to unmask]> Sent: Thursday, February 21, 2002 11:07 PM Subject: feedback on selegiline (eldepryl) > I would love to have some feedback from any of you who have been or are now taking selegiline. At a support group I attended several people referred to bad experiences they had while taking it. I'm just curious as to whether some of my side effects are related to it. I can't seem to find much info on it , or at least much I can understand, so I decided to skip the medical journal stuff and go to the people who should know best. Thanks. > Debra > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn