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Brain patch suspected of spreading CJD

Last Updated Tue, 26 Mar 2002 23:57:03 - TORONTO - The use of human tissue
during surgery is putting Canadians at risk of contracting brain-wasting
Creutzfeldt-Jakob disease, researchers say.

What has them concerned is a patch of tissue called dura matter, taken from
human cadavers and used to seal incisions during brain surgery.

"We estimate that probably somewhere between two and 400 grafts per year
are used in Canada," says Richard Moulton of the Canadian Neurosurgical
Society.

Moulton says his group believes the tissue patch should be banned to reduce
the risk of accidental transmission of CJD.

Human dura matter is believed to have caused more than 114 cases of CJD
worldwide, including four in Canada.

At age three, Dominique Roy-Regimbald underwent surgery in Montreal to
remove a brain tumor. To repair the brain membrane, doctors used a Lyodura
patch made in Germany.

Dominique's family believes the patch carried the infectious agent that
caused him to develop CJD. He died of the disease in 1999, at age 14.
Health Canada had warned hospitals of the risk one year before Dominique's
surgery.

"There are people in Canada who have received it after the warning," says
Dr. Neil Cashman, a CJD researcher at the University of Toronto.

Written by CBC News Online staff
http://cbc.ca/stories/2002/03/26/cjd_tissue020326

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