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Yes, no question about it--My sister (young onset PD) is now 40 and diagnosed at 28. In her case, there is a significant difference in symptom severity which coincides with her monthly cycle. To aid with this, she is currently on estrogen (birth control pill) EVERY DAY--with no placebo. Interestingly, becuase she also presents with significant PD drug induced psychiatric symptoms, this steady input of estrogen into her system also really helps keeping this aspect much more controlled. So-- the estrogen therapy is making a difference for her in both physcial AND psychiatric ways. --Sharon ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn