FROM: The Weekend Australian April 6, 2002, Saturday HEADLINE: States agree to PM's stem-cell limits - THE LEADERS DECIDE BYLINE: John Kerin THE procedure that produced Dolly the sheep, and could potentially offer breakthrough treatments for genetic diseases, will be banned in Australia under a national agreement decided yesterday. The states signed up to John Howard's plan to give scientists the right to use spare embryos from in-vitro fertilisation programs for research into debilitating illnesses such as Alzheimer's and Parkinson's diseases and diabetes. But the legislation will include a ban on "therapeutic cloning", which leading researchers warned yesterday would leave Australia falling behind in research. In a deal struck at the Council of Australian Governments meeting in Canberra, it was decided scientists would have access to about 70,000 existing embryos stored in medical facility freezers around the country that had been deemed as surplus by donors. The embryos, which can be stored for up to 10 years in most states, are destroyed if not used, and donors must give permission for their use. Dolly the sheep was the first animal to be cloned using genetically matched embryos involving a process known as "somatic-cell nuclear transfer". In humans, "therapeutic cloning" involves implanting a patient's adult cells into an egg cell to reproduce embryonic stem cells. Australia's leading stem-cell researcher, Alan Trounson, warned last night the Howard decision could leave Australia lagging and force patients to travel to Britain, where such research was allowed. "If British researchers are able to produce breakthroughs in this line of research, what are we going to do?" Professor Trounson said. John White, of the Australian Academy of Science, welcomed the national PAGE 2 The Weekend Australian April 6, 2002, Saturday agreement but also criticised aspects of the decision. "There are other options, but therapeutic cloning offers possibilities," he said. Responding to Professor White's comments, Mr Howard said on Sydney radio: "He is not speaking for the entire scientific community ... if you want to quote scientists, Dr Trounson has broadly welcomed the proposals that I outlined yesterday." Government sources suggested therapeutic cloning would be banned because it involved the creation of an embryo for research purposes and raised sensitive issues of respect for human life. Earlier, Mr Howard declared the states and the commonwealth had reached a "magnificent and enlightened outcome" on stem-cell research. The states and the commonwealth are expected to have complementary uniform legislation in place by June. After initially having rejected Mr Howard's package on the eve of the COAG meeting, the states secured two minor concessions from Mr Howard yesterday. Embryo donors only have to give general consent. Mr Howard wanted experimentation restricted to existing surplus embryos but this restriction expires in three years. An ethics committee has been established to examine a regime to ensure embryos are not created for research purposes. THE GUIDELINES - Uniform federal, state and territory laws. Conscience votes in federal and state parliaments allowed by major parties - to be introduced from June 2002. - Research permitted only on surplus IVF embryos now but this will lapse on April 5, 2005. - Embryo donors to give permission for research - Health Ethics Committee to look at regime to ensure embryos are not created for the purpose of scientific research - Ban on all forms of human cloning including so-called 'therapeutic cloning' - Laws to be reviewd in three years - National Health and Medical Research Council to oversee research ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn