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For what it is worth, here is our experience with CR. Caused unpredictable a wild swings in On and Off cycles. By discontinuing the CR and raising the Snippet to every 3/4 hours we were able to smooth the response. Perhaps there are some people who should stay away from CR, we are definitely one of those types. We used comtan along with Sinemet and found a world of difference. Of course we all know hat no two Parkies respond the same, but as I said "For what it is worth". Ron heimback ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn