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I was diagnosed with PD about four years ago when a tremor became noticeable on my left side. I began taking Sinemet at that time. Two years ago my neuro started me on Mirapex in addition to the Sinemet. I am a strong believer in the effects of Mirapex having had no marked change in my symptoms in the past six months nor for that matter since I began taking Mirapex. I only see the neuro every six months having had the most recent visit on April 5. He gave me the routine tests and stated my gait has not worsened nor had I lost any control of my extremities. I also have rheumatoid arthritis and find that much more difficult to manage than the PD. I cannot state with authority that Mirapex has slowed the progression but since my neuro is the director of the Parkinson's Ass'n of Greater Orlando and is closely associated with Dr. Lieberman, the National Director, I must lean towards the agonist as my "miracle" drug. The imput by members of the "list" is invaluable to me just as it is to so many of you around the world. Marilyn, [log in to unmask] ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn