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Hi, in my humble opinion, please consider going to another neuro. I've had one incompetent, and that was a pain. Adjusting the medications is tricky, and with the knowledge of a competent neurologist specialised in movement disorders it is easier to get it right... Also, try to take the medication 15 minutes before eating, no more, no less. This helps to ensure that the full dose is absorbed by the body without interference from the food. Right now I'm on Madopar Quick Mite 12,5/50 (almost identical to Sinemet, but made by Roche, easily dissolved in water and quickly absorbed by the body), I take 1.5 Madopar as a "kick start" in the morning and then 1 every two hours until I go to bed. When I go to bed I take one 25/100 "CR" capsule. Every eight hours I take 1 Tasmar, 3 Mirapex 0.25mg, 1 Motilium (domperidonum 10mg, against nausea from apomorphine). Apomorphine injections if I experience a sudden "off". If I want sleep more than 6 hours, I still set my alarm clock at six hours, take 1.5 Madopar together with the other pills and go back to sleep, otherwise I have to be fed with the pills and it takes me ages to be reasonably mobile. My cellular phone has a built in timer, I set it to two hours every time I have taken the pills to make sure I remember to take the next dose on time... Hope that helps, John 18/26/33 ----- Original Message ----- From: "patandpaula" <[log in to unmask]> To: <[log in to unmask]> Sent: Sunday, May 12, 2002 11:21 PM Subject: Re: frequency of sinemet doses > david, do you take them until you go to bed at night? do you take one at a > time? so is that about four times a day you are taking them? thanks a lot > paula oh yes, after your last dose of the day, about how long is it before > you go to bed for the night? thanks and im sorry if this sounding > personal, but im trying to get my mother on some kind of a regime and i dont > know where to start. > ----- Original Message ----- > From: "David Moreland" <[log in to unmask]> > To: <[log in to unmask]> > Sent: Sunday, May 12, 2002 2:42 PM > Subject: frequency of sinemet doses > > > > I take sinemet 50/200 CR and it works gfor me to take them every 4 houres > > saeting > > at 6:00 AM. It is my understanding that the standard 25/100 will last > about > > two hours or with Comtan they might last three hours. Now this is hiw they > > work for me. i have tried just about every combination of PD medication > and > > this is what works most consistently for me. I have only been a Parkie for > > 15 years. > > > > At 02:20 PM 5/12/2002 -0500, you wrote: > > >hi would someone tell me please how you space your sinimet doses?? four > > >hours apart, six hours? or what? i know it works differently for every > > >individual, but i would just like to get a general idea of what works for > > >some of you please. my mother was taking hers seven or eight hours apart > > >and of that is not working. thanks a lot paula ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn