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Jann

Many thanks for this information

dhiso

Julie

----- Original Message -----
From: "Jann Bell" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Tuesday, May 21, 2002 4:31 PM
Subject: Re: IHT: Hints of a Parkinson's 'cluster'


> Here is a recent post from a friend. It mainly addresses prevention, but
> maybe it has benefits for PD sufferers as well.
>
> 1: Am J Epidemiol  2002 Apr 15;155(8):732-8
>
> Parkinson's disease risks associated with cigarette smoking, alcohol
> consumption, and caffeine intake.
>
> Checkoway H, Powers K, Smith-Weller T, Franklin GM, Longstreth WT Jr,
> Swanson
> PD.
>
> University of Washington, School of Public Health and Community Medicine,
> Department of Environmental Health, Seattle, WA 98195, USA.
> [log in to unmask]
>
> A reduced risk for Parkinson's disease (PD) among cigarette smokers has
been
> observed consistently during the past 30 years. Recent evidence suggests
> that
> caffeine may also be protective. Findings are presented regarding
> associations
> of PD with smoking, caffeine intake, and alcohol consumption from a
> case-control
> study conducted in western Washington State in 1992-2000. Incident PD
cases
> (n =
> 210) and controls (n = 347), frequency matched on gender and age were
> identified
> from enrollees of the Group Health Cooperative health maintenance
> organization.
> Exposure data were obtained by in-person questionnaires. Ever having
smoked
> cigarettes was associated with a reduced risk of PD (odds ratio (OR) =
0.5,
> 95%
> confidence interval (CI): 0.4, 0.8). A stronger relation was found among
> current
> smokers (OR = 0.3, 95% CI: 0.1, 0.7) than among ex-smokers (OR = 0.6, 95%
> CI:
> 0.4, 0.9), and there was an inverse gradient with pack-years smoked (trend
p
> <
> 0.001). No associations were detected for coffee consumption or total
> caffeine
> intake or for alcohol consumption. However, reduced risks were observed
for
> consumption of 2 cups/day or more of tea (OR = 0.4, 95% CI: 0.2, 0.9) and
> two or
> more cola drinks/day (OR = 0.6, 95% CI: 0.3, 1.4). The associations for
tea
> and
> cola drinks were not confounded by smoking or coffee consumption.
>
> PMID: 11943691 [PubMed - indexed for MEDLINE]
>
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