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Raj: Being you mentioned Dr. Perlmutter, I was a patient of his during the winter months that I spent in Florida. He seemed to be very knowledgeable Dr. three months ago I started on Glutathione here in Michigan. I took the intravenous injections twice a week for six weeks without a positive effect. I guess I'm one of the unfortunate ones. It sounds like your taking good care of yourself, by your regimen. Keep up the good work. Ervin McCarthy ----- Original Message ----- From: "Brightline" <[log in to unmask]> To: <[log in to unmask]> Sent: Tuesday, June 04, 2002 4:33 PM Subject: Raj/glutathione > Hi! Ervin & Rayilyn: > I have never tried Sinemet, eventhough I have a prescrition for it. I > am sure it will be of help, based on the nearly 30 years of experience with > levodopa. However, I am still reluctant to try it due to its mile long list > of side effects, (however low freqnuency of occurrence they might be) and am > keeping it handy as a last resort. I may not be surprised if for some > people it does not work. Even in the NPF info it states that L-dopa has > been shown to be harmful to dopamine producing cells in vitro and in vivio > in animal studies. It states that L-dopa may or may not be beneficial! > But, both Dr. AH Rajput and Dr. Jancovics believe, however, it is not > harmful to humans. This is supported by the fact that since the > introduction of L-dopa or sinemet, people with PD have been living longer. > In the article by Dr. Perlmuter, it says that both dopmine and > glutathione are low in PD patients. For some reason L-dopa application has > caught up and the fate of glutatione deficiency has been left hanging in the > air. I have been taking glutathione - reduced for the last week or so. I > definitely feel some improvement in my condition, good enough to postpone > taking sinement. I do not know how to quantitate my results. I am not sure > how long this beneficial effect will last. I would like to know your > experience with Glutathione. One should not expect miracles, since whatever > is lost is lost for ever. I only hope this will slow down the prgression of > PD, as evidencd by decrease in and not total elimnation of the symptoms of > PD. > > First thing in the morning I take a cup of greentea with a tablespoon of > honey with no milk or sugar. Some times I include about 25-50 mg of > caffeine pill along with my tea. > I am taking glutathione along with phosphatydilserine, B6, B12, Folate, > Vitamin E and about 1/3 pill of multivitamain (senior edition with less > amount of iron) every day in the morning just before breakfast. > My breakfast consists of bran flakes, about 12 fresh almonds, a pinch > of peeled pumpkin seeds (for my prostate problems), and a spoon full of > powdered flax seed; this also includes one cup of a fruit juice cocktail > (1:1 mix of orange and tomato juices with a small amount of blue berry > juice). > (I am a little bit uncertain about the benefit of blue berry or bb juice > for PD patients, since aluminum sulfate is used as a fertlizer for blue > berry plants. Aluminum has been implicated in PD and in Alzheimer's. Does > anybody know the aluminum content of blue berries? So do I with regard to > commercial yogurts. In 1960s and 70s, the preservative in commercial > yogurt called MSG or monosodium glutamate [also earlier used in Chinese > cooking] has been a contentious issue since in animal studies this caused > serious nervous system disorders. Some yogurt products still state 1-2% MG > on their stickers. I often wonder is MG is the same as MSG!) Sorry for > being paranoid. It is better to be careful, than feeling sorry later. > > For lunch and supper, I take pretty much anything, except that I make > sure to take a good dose of fresh vegetables and fruits. > Of course, I also include at least 20-30 min of exercise every morning. > > There is no guarantee that what might seem to work for me may work for > everybody, since as you well know, PD is a personalized disease, often with > comomn symptoms that show up at variable rate and similarly, the resonse to > any drug is also variable between individals. YOU SHOULD DEFINIELY CONSULT > WITH YOR DOCTOR ON ANYTHING YOU TAKE OR DO FOR YOUR PD. > > QUESTION: > If both dopamine and glutathione are low in PD patients, I would ask > myself if it would make sense to take glutathione in addition to sinemet. > BUT, I DON'T HAVE THE ANSWER FOR THIS QUESTION. SO PLEASE DO NOT TRY. > SOME TIMES, THERE COULD BE UNFORSEEN HARMFUL EFFECTS IF TWO DRUGS ARE > COMBINED. > GOOD EXAMPLE: A CLINICAL TRIAL WAS STOPPED HALFWAY IN ENGLAND RECENTLY > SINCE IT INCREASED MORTALITY RATE AMONG THE GROUP OF PD PATIENTS THAT WERE > GIVEN L-DOPA (SINEMET?) AND SELGELINE! > > > Raj > [log in to unmask] > ----- Original Message ----- > From: "Ervin McCarthy" <[log in to unmask]> > To: <[log in to unmask]> > Sent: Tuesday, June 04, 2002 9:33 PM > Subject: Re: Raj/glutathione > > > > Rayilyn, I have gotten the same results from Sinemet on three occasions. > I > > was curious if anyone else had the same results. Now I know. Thank you. > > Ervin McCarthy > > ----- Original Message ----- > > From: "Rayilyn Brown" <[log in to unmask]> > > To: <[log in to unmask]> > > Sent: Monday, June 03, 2002 9:39 PM > > Subject: Re: Raj/glutathione > > > > > > > Raj, Thanks for the info on glutathione...that it is a small molecule. > > I'm > > > going to try the oral glutathione first, before intravenous. Sinemet > > never > > > helped me much and after a year made dystonia in my feet unbearable. > > I''ve > > > tried it again 3 times with same result. Rayilyn > > > > > > ---------------------------------------------------------------------- > > > To sign-off Parkinsn send a message to: > > mailto:[log in to unmask] > > > In the body of the message put: signoff parkinsn > > > > ---------------------------------------------------------------------- > > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > > In the body of the message put: signoff parkinsn > > > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn