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Erwin, I also met a person that was taking glutathione intravenously. This did not do anything for him either. This person was taking it for 2 years without any other Parkinson drugs. He was devastated. I wrote about this experience previously. From all the research I have done on the subject, if this is taken orally, the impact would be even less as gluthatione does not absorb very well orally. Some people may experience placebo from different supplements for a while. I do not want to discourage anybody from trying. Emily ----- Original Message ----- From: "Ervin McCarthy" <[log in to unmask]> To: <[log in to unmask]> Sent: Thursday, June 06, 2002 7:10 PM Subject: Re: Raj/glutathione > Raj: > Being you mentioned Dr. Perlmutter, I was a patient of his during the winter > months that I spent in Florida. He seemed to be very knowledgeable Dr. > three months ago I started on Glutathione here in Michigan. I took the > intravenous injections twice a week for six weeks without a positive effect. > I guess I'm one of the unfortunate ones. > It sounds like your taking good care of yourself, by your regimen. Keep up > the good work. > > Ervin McCarthy > ----- Original Message ----- > From: "Brightline" <[log in to unmask]> > To: <[log in to unmask]> > Sent: Tuesday, June 04, 2002 4:33 PM > Subject: Raj/glutathione > > > > Hi! Ervin & Rayilyn: > > I have never tried Sinemet, eventhough I have a prescrition for it. I > > am sure it will be of help, based on the nearly 30 years of experience > with > > levodopa. However, I am still reluctant to try it due to its mile long > list > > of side effects, (however low freqnuency of occurrence they might be) and > am > > keeping it handy as a last resort. I may not be surprised if for some > > people it does not work. Even in the NPF info it states that L-dopa has > > been shown to be harmful to dopamine producing cells in vitro and in vivio > > in animal studies. It states that L-dopa may or may not be beneficial! > > But, both Dr. AH Rajput and Dr. Jancovics believe, however, it is not > > harmful to humans. This is supported by the fact that since the > > introduction of L-dopa or sinemet, people with PD have been living longer. > > In the article by Dr. Perlmuter, it says that both dopmine and > > glutathione are low in PD patients. For some reason L-dopa application > has > > caught up and the fate of glutatione deficiency has been left hanging in > the > > air. I have been taking glutathione - reduced for the last week or so. I > > definitely feel some improvement in my condition, good enough to postpone > > taking sinement. I do not know how to quantitate my results. I am not > sure > > how long this beneficial effect will last. I would like to know your > > experience with Glutathione. One should not expect miracles, since > whatever > > is lost is lost for ever. I only hope this will slow down the prgression > of > > PD, as evidencd by decrease in and not total elimnation of the symptoms of > > PD. > > > > First thing in the morning I take a cup of greentea with a tablespoon > of > > honey with no milk or sugar. Some times I include about 25-50 mg of > > caffeine pill along with my tea. > > I am taking glutathione along with phosphatydilserine, B6, B12, > Folate, > > Vitamin E and about 1/3 pill of multivitamain (senior edition with less > > amount of iron) every day in the morning just before breakfast. > > My breakfast consists of bran flakes, about 12 fresh almonds, a pinch > > of peeled pumpkin seeds (for my prostate problems), and a spoon full of > > powdered flax seed; this also includes one cup of a fruit juice cocktail > > (1:1 mix of orange and tomato juices with a small amount of blue berry > > juice). > > (I am a little bit uncertain about the benefit of blue berry or bb > juice > > for PD patients, since aluminum sulfate is used as a fertlizer for blue > > berry plants. Aluminum has been implicated in PD and in Alzheimer's. > Does > > anybody know the aluminum content of blue berries? So do I with regard to > > commercial yogurts. In 1960s and 70s, the preservative in commercial > > yogurt called MSG or monosodium glutamate [also earlier used in Chinese > > cooking] has been a contentious issue since in animal studies this caused > > serious nervous system disorders. Some yogurt products still state 1-2% > MG > > on their stickers. I often wonder is MG is the same as MSG!) Sorry for > > being paranoid. It is better to be careful, than feeling sorry later. > > > > For lunch and supper, I take pretty much anything, except that I make > > sure to take a good dose of fresh vegetables and fruits. > > Of course, I also include at least 20-30 min of exercise every > morning. > > > > There is no guarantee that what might seem to work for me may work for > > everybody, since as you well know, PD is a personalized disease, often > with > > comomn symptoms that show up at variable rate and similarly, the resonse > to > > any drug is also variable between individals. YOU SHOULD DEFINIELY > CONSULT > > WITH YOR DOCTOR ON ANYTHING YOU TAKE OR DO FOR YOUR PD. > > > > QUESTION: > > If both dopamine and glutathione are low in PD patients, I would ask > > myself if it would make sense to take glutathione in addition to sinemet. > > BUT, I DON'T HAVE THE ANSWER FOR THIS QUESTION. SO PLEASE DO NOT TRY. > > SOME TIMES, THERE COULD BE UNFORSEEN HARMFUL EFFECTS IF TWO DRUGS ARE > > COMBINED. > > GOOD EXAMPLE: A CLINICAL TRIAL WAS STOPPED HALFWAY IN ENGLAND > RECENTLY > > SINCE IT INCREASED MORTALITY RATE AMONG THE GROUP OF PD PATIENTS THAT WERE > > GIVEN L-DOPA (SINEMET?) AND SELGELINE! > > > > > > Raj > > [log in to unmask] > > ----- Original Message ----- > > From: "Ervin McCarthy" <[log in to unmask]> > > To: <[log in to unmask]> > > Sent: Tuesday, June 04, 2002 9:33 PM > > Subject: Re: Raj/glutathione > > > > > > > Rayilyn, I have gotten the same results from Sinemet on three occasions. > > I > > > was curious if anyone else had the same results. Now I know. Thank > you. > > > Ervin McCarthy > > > ----- Original Message ----- > > > From: "Rayilyn Brown" <[log in to unmask]> > > > To: <[log in to unmask]> > > > Sent: Monday, June 03, 2002 9:39 PM > > > Subject: Re: Raj/glutathione > > > > > > > > > > Raj, Thanks for the info on glutathione...that it is a small > molecule. > > > I'm > > > > going to try the oral glutathione first, before intravenous. Sinemet > > > never > > > > helped me much and after a year made dystonia in my feet unbearable. > > > I''ve > > > > tried it again 3 times with same result. Rayilyn > > > > > > > > ---------------------------------------------------------------------- > > > > To sign-off Parkinsn send a message to: > > > mailto:[log in to unmask] > > > > In the body of the message put: signoff parkinsn > > > > > > ---------------------------------------------------------------------- > > > To sign-off Parkinsn send a message to: > > mailto:[log in to unmask] > > > In the body of the message put: signoff parkinsn > > > > > > > ---------------------------------------------------------------------- > > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > > In the body of the message put: signoff parkinsn > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn