Emily: I am sorry to hear that your friend also did not have a good response from iv glutahione. And you tell me that oral administration does not yield good results due to absorption problem. Can one try higher doses if it is just a problem of absorption? If you see my response to Ervin, so far (only about 10 days), I am having relatively satisfactory effect from Glutathione orally taken. I shall watch myself carefully for another three to four weeks and let you know. I also do not expect complete cure from glutathione. I am hoping that with the reduction in the severity of the symptoms (if it persists for longer duration) , there shall be an added benefit of retardation in the progression of PD. Raj [log in to unmask] ********** ----- Original Message ----- From: "Emily and Julian Brinac" <[log in to unmask]> To: <[log in to unmask]> Sent: Thursday, June 06, 2002 7:10 PM Subject: Re: Raj/glutathione > Erwin, > I also met a person that was taking glutathione intravenously. This did > not do anything for him either. This person was taking it for 2 years > without any other Parkinson drugs. He was devastated. I wrote about this > experience previously. From all the research I have done on the subject, > if this is taken orally, the impact would be even less as gluthatione > does not absorb very well orally. Some people may experience placebo > from different supplements for a while. I do not want to discourage > anybody from trying. > Emily > ----- Original Message ----- > From: "Ervin McCarthy" <[log in to unmask]> > To: <[log in to unmask]> > Sent: Thursday, June 06, 2002 7:10 PM > Subject: Re: Raj/glutathione > > > > Raj: > > Being you mentioned Dr. Perlmutter, I was a patient of his during the > winter > > months that I spent in Florida. He seemed to be very knowledgeable > Dr. > > three months ago I started on Glutathione here in Michigan. I took > the > > intravenous injections twice a week for six weeks without a positive > effect. > > I guess I'm one of the unfortunate ones. > > It sounds like your taking good care of yourself, by your regimen. > Keep up > > the good work. > > > > Ervin McCarthy > > ----- Original Message ----- > > From: "Brightline" <[log in to unmask]> > > To: <[log in to unmask]> > > Sent: Tuesday, June 04, 2002 4:33 PM > > Subject: Raj/glutathione > > > > > > > Hi! Ervin & Rayilyn: > > > I have never tried Sinemet, eventhough I have a prescrition for > it. I > > > am sure it will be of help, based on the nearly 30 years of > experience > > with > > > levodopa. However, I am still reluctant to try it due to its mile > long > > list > > > of side effects, (however low freqnuency of occurrence they might > be) and > > am > > > keeping it handy as a last resort. I may not be surprised if for > some > > > people it does not work. Even in the NPF info it states that L-dopa > has > > > been shown to be harmful to dopamine producing cells in vitro and in > vivio > > > in animal studies. It states that L-dopa may or may not be > beneficial! > > > But, both Dr. AH Rajput and Dr. Jancovics believe, however, it is > not > > > harmful to humans. This is supported by the fact that since the > > > introduction of L-dopa or sinemet, people with PD have been living > longer. > > > In the article by Dr. Perlmuter, it says that both dopmine and > > > glutathione are low in PD patients. For some reason L-dopa > application > > has > > > caught up and the fate of glutatione deficiency has been left > hanging in > > the > > > air. I have been taking glutathione - reduced for the last week or > so. I > > > definitely feel some improvement in my condition, good enough to > postpone > > > taking sinement. I do not know how to quantitate my results. I am > not > > sure > > > how long this beneficial effect will last. I would like to know > your > > > experience with Glutathione. One should not expect miracles, since > > whatever > > > is lost is lost for ever. I only hope this will slow down the > prgression > > of > > > PD, as evidencd by decrease in and not total elimnation of the > symptoms of > > > PD. > > > > > > First thing in the morning I take a cup of greentea with a > tablespoon > > of > > > honey with no milk or sugar. Some times I include about 25-50 mg > of > > > caffeine pill along with my tea. > > > I am taking glutathione along with phosphatydilserine, B6, B12, > > Folate, > > > Vitamin E and about 1/3 pill of multivitamain (senior edition with > less > > > amount of iron) every day in the morning just before breakfast. > > > My breakfast consists of bran flakes, about 12 fresh almonds, a > pinch > > > of peeled pumpkin seeds (for my prostate problems), and a spoon full > of > > > powdered flax seed; this also includes one cup of a fruit juice > cocktail > > > (1:1 mix of orange and tomato juices with a small amount of blue > berry > > > juice). > > > (I am a little bit uncertain about the benefit of blue berry or > bb > > juice > > > for PD patients, since aluminum sulfate is used as a fertlizer for > blue > > > berry plants. Aluminum has been implicated in PD and in > Alzheimer's. > > Does > > > anybody know the aluminum content of blue berries? So do I with > regard to > > > commercial yogurts. In 1960s and 70s, the preservative in > commercial > > > yogurt called MSG or monosodium glutamate [also earlier used in > Chinese > > > cooking] has been a contentious issue since in animal studies this > caused > > > serious nervous system disorders. Some yogurt products still state > 1-2% > > MG > > > on their stickers. I often wonder is MG is the same as MSG!) Sorry > for > > > being paranoid. It is better to be careful, than feeling sorry > later. > > > > > > For lunch and supper, I take pretty much anything, except that I > make > > > sure to take a good dose of fresh vegetables and fruits. > > > Of course, I also include at least 20-30 min of exercise every > > morning. > > > > > > There is no guarantee that what might seem to work for me may > work for > > > everybody, since as you well know, PD is a personalized disease, > often > > with > > > comomn symptoms that show up at variable rate and similarly, the > resonse > > to > > > any drug is also variable between individals. YOU SHOULD DEFINIELY > > CONSULT > > > WITH YOR DOCTOR ON ANYTHING YOU TAKE OR DO FOR YOUR PD. > > > > > > QUESTION: > > > If both dopamine and glutathione are low in PD patients, I would > ask > > > myself if it would make sense to take glutathione in addition to > sinemet. > > > BUT, I DON'T HAVE THE ANSWER FOR THIS QUESTION. SO PLEASE DO > NOT TRY. > > > SOME TIMES, THERE COULD BE UNFORSEEN HARMFUL EFFECTS IF TWO DRUGS > ARE > > > COMBINED. > > > GOOD EXAMPLE: A CLINICAL TRIAL WAS STOPPED HALFWAY IN ENGLAND > > RECENTLY > > > SINCE IT INCREASED MORTALITY RATE AMONG THE GROUP OF PD PATIENTS > THAT WERE > > > GIVEN L-DOPA (SINEMET?) AND SELGELINE! > > > > > > > > > Raj > > > [log in to unmask] > > > ----- Original Message ----- > > > From: "Ervin McCarthy" <[log in to unmask]> > > > To: <[log in to unmask]> > > > Sent: Tuesday, June 04, 2002 9:33 PM > > > Subject: Re: Raj/glutathione > > > > > > > > > > Rayilyn, I have gotten the same results from Sinemet on three > occasions. > > > I > > > > was curious if anyone else had the same results. Now I know. > Thank > > you. > > > > Ervin McCarthy > > > > ----- Original Message ----- > > > > From: "Rayilyn Brown" <[log in to unmask]> > > > > To: <[log in to unmask]> > > > > Sent: Monday, June 03, 2002 9:39 PM > > > > Subject: Re: Raj/glutathione > > > > > > > > > > > > > Raj, Thanks for the info on glutathione...that it is a small > > molecule. > > > > I'm > > > > > going to try the oral glutathione first, before intravenous. > Sinemet > > > > never > > > > > helped me much and after a year made dystonia in my feet > unbearable. > > > > I''ve > > > > > tried it again 3 times with same result. Rayilyn > > > > > > > > > > > ---------------------------------------------------------------------- > > > > > To sign-off Parkinsn send a message to: > > > > mailto:[log in to unmask] > > > > > In the body of the message put: signoff parkinsn > > > > > > > > > ---------------------------------------------------------------------- > > > > To sign-off Parkinsn send a message to: > > > mailto:[log in to unmask] > > > > In the body of the message put: signoff parkinsn > > > > > > > > > > > ---------------------------------------------------------------------- > > > To sign-off Parkinsn send a message to: > > mailto:[log in to unmask] > > > In the body of the message put: signoff parkinsn > > > > ---------------------------------------------------------------------- > > To sign-off Parkinsn send a message to: > mailto:[log in to unmask] > > In the body of the message put: signoff parkinsn > > ---------------------------------------------------------------------- > To sign-off Parkinsn send a message to: mailto:[log in to unmask] > In the body of the message put: signoff parkinsn > ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn