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Emily:
    I am sorry to hear that your friend also did not have a good response
from iv glutahione.      And you tell me that oral administration does not
yield good results due to absorption problem. Can one try higher doses if it
is just a problem of absorption?
    If you see my response to Ervin, so far (only about 10 days), I am
having relatively satisfactory effect from Glutathione orally taken.  I
shall watch myself carefully for another three to four weeks and let you
know.  I also do not expect complete cure from glutathione.  I am hoping
that with the reduction in the severity of the symptoms (if it persists for
longer duration) , there shall be an added benefit of retardation in the
progression of PD.
    Raj
    [log in to unmask]
**********
----- Original Message -----
From: "Emily and Julian Brinac" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Thursday, June 06, 2002 7:10 PM
Subject: Re: Raj/glutathione


> Erwin,
> I also met a person that was taking glutathione intravenously. This did
> not do anything for him either. This person was taking it for 2 years
> without any other Parkinson drugs. He was devastated. I wrote about this
> experience previously. From all the research I have done on the subject,
> if this is taken orally, the impact would be even less as gluthatione
> does not absorb very well orally. Some people may experience placebo
> from different supplements for a while. I do not want to discourage
> anybody from trying.
> Emily
> ----- Original Message -----
> From: "Ervin McCarthy" <[log in to unmask]>
> To: <[log in to unmask]>
> Sent: Thursday, June 06, 2002 7:10 PM
> Subject: Re: Raj/glutathione
>
>
> > Raj:
> > Being you mentioned Dr. Perlmutter, I was a patient of his during the
> winter
> > months that I spent in Florida.  He seemed to be very knowledgeable
> Dr.
> > three months ago I started on Glutathione here in Michigan.  I took
> the
> > intravenous injections twice a week for six weeks without a positive
> effect.
> > I guess I'm one of the unfortunate ones.
> > It sounds like your taking good care of yourself, by your regimen.
> Keep up
> > the good work.
> >
> > Ervin McCarthy
> > ----- Original Message -----
> > From: "Brightline" <[log in to unmask]>
> > To: <[log in to unmask]>
> > Sent: Tuesday, June 04, 2002 4:33 PM
> > Subject: Raj/glutathione
> >
> >
> > > Hi! Ervin & Rayilyn:
> > >     I have never tried Sinemet, eventhough I have a prescrition for
> it.  I
> > > am sure it will be of help, based on the nearly 30 years of
> experience
> > with
> > > levodopa.  However, I am still reluctant to try it due to its mile
> long
> > list
> > > of side effects, (however low freqnuency of occurrence they might
> be) and
> > am
> > > keeping it handy as a last resort.  I may not be surprised if for
> some
> > > people it does not work.  Even in the NPF info it states that L-dopa
> has
> > > been shown to be harmful to dopamine producing cells in vitro and in
> vivio
> > > in animal studies.  It states that L-dopa may or may not be
> beneficial!
> > > But, both Dr. AH Rajput and Dr. Jancovics believe, however, it is
> not
> > > harmful to humans.  This is supported by the fact that since the
> > > introduction of L-dopa or sinemet, people with PD have been living
> longer.
> > >     In the article by Dr. Perlmuter, it says that both dopmine and
> > > glutathione are low in PD patients.  For some reason L-dopa
> application
> > has
> > > caught up and the fate of glutatione deficiency has been left
> hanging in
> > the
> > > air.  I have been taking glutathione - reduced for the last week or
> so.  I
> > > definitely feel some improvement in my condition, good enough to
> postpone
> > > taking sinement.  I do not know how to quantitate my results. I am
> not
> > sure
> > > how long this beneficial effect will last.  I would like to know
> your
> > > experience with Glutathione.  One should not expect miracles, since
> > whatever
> > > is lost is lost for ever.  I only hope this will slow down the
> prgression
> > of
> > > PD, as evidencd by decrease in and not total elimnation of the
> symptoms of
> > > PD.
> > >
> > >     First thing in the morning I take a cup of greentea with a
> tablespoon
> > of
> > > honey with  no milk or sugar.   Some times I include about 25-50 mg
> of
> > > caffeine pill along with my tea.
> > >     I am taking glutathione along with phosphatydilserine, B6, B12,
> > Folate,
> > > Vitamin E and about 1/3 pill of multivitamain (senior edition with
> less
> > > amount of iron) every day in the morning just before breakfast.
> > >     My breakfast consists of bran flakes, about  12 fresh almonds, a
> pinch
> > > of peeled pumpkin seeds (for my prostate problems), and a spoon full
> of
> > > powdered flax seed; this also includes one cup of a fruit juice
> cocktail
> > > (1:1 mix of orange and tomato juices with a small amount of blue
> berry
> > > juice).
> > >     (I am a little bit uncertain about the benefit of blue berry or
> bb
> > juice
> > > for PD patients, since aluminum sulfate is used as a fertlizer for
> blue
> > > berry plants.  Aluminum has been implicated in PD and in
> Alzheimer's.
> > Does
> > > anybody know the aluminum content of blue berries? So do I with
> regard to
> > > commercial yogurts.  In 1960s and 70s,  the preservative in
> commercial
> > > yogurt called MSG or monosodium glutamate [also earlier used in
> Chinese
> > > cooking] has been a contentious issue since in animal studies this
> caused
> > > serious nervous system disorders.  Some yogurt products still state
> 1-2%
> > MG
> > > on their stickers.  I often wonder is MG is the same as MSG!)  Sorry
> for
> > > being paranoid.  It is better to be careful, than feeling sorry
> later.
> > >
> > >     For lunch and supper, I take pretty much anything, except that I
> make
> > > sure to take a good dose of fresh vegetables and fruits.
> > >     Of course, I also include at least 20-30 min of exercise every
> > morning.
> > >
> > >     There is no guarantee that what might seem to work for me may
> work for
> > > everybody, since as you well know, PD is a personalized disease,
> often
> > with
> > > comomn symptoms that show up at variable rate and similarly, the
> resonse
> > to
> > > any drug is also variable between individals.  YOU SHOULD DEFINIELY
> > CONSULT
> > > WITH YOR DOCTOR ON ANYTHING YOU TAKE OR DO FOR YOUR PD.
> > >
> > > QUESTION:
> > >     If both dopamine and glutathione are low in PD patients, I would
> ask
> > > myself if it would make sense to take glutathione in addition to
> sinemet.
> > >     BUT, I DON'T HAVE THE ANSWER FOR THIS QUESTION.  SO PLEASE DO
> NOT TRY.
> > > SOME TIMES, THERE COULD BE UNFORSEEN HARMFUL EFFECTS IF TWO DRUGS
> ARE
> > > COMBINED.
> > >     GOOD EXAMPLE:  A CLINICAL TRIAL WAS STOPPED HALFWAY IN ENGLAND
> > RECENTLY
> > > SINCE IT INCREASED MORTALITY RATE AMONG THE GROUP OF PD PATIENTS
> THAT WERE
> > > GIVEN L-DOPA (SINEMET?) AND SELGELINE!
> > >
> > >
> > >     Raj
> > > [log in to unmask]
> > > ----- Original Message -----
> > > From: "Ervin McCarthy" <[log in to unmask]>
> > > To: <[log in to unmask]>
> > > Sent: Tuesday, June 04, 2002 9:33 PM
> > > Subject: Re: Raj/glutathione
> > >
> > >
> > > > Rayilyn, I have gotten the same results from Sinemet on three
> occasions.
> > > I
> > > > was curious if anyone else had the same results.  Now I know.
> Thank
> > you.
> > > > Ervin McCarthy
> > > > ----- Original Message -----
> > > > From: "Rayilyn Brown" <[log in to unmask]>
> > > > To: <[log in to unmask]>
> > > > Sent: Monday, June 03, 2002 9:39 PM
> > > > Subject: Re: Raj/glutathione
> > > >
> > > >
> > > > > Raj,  Thanks for the info on glutathione...that it is a small
> > molecule.
> > > > I'm
> > > > > going to try the oral glutathione first, before intravenous.
> Sinemet
> > > > never
> > > > > helped me much and after a year made dystonia in my feet
> unbearable.
> > > > I''ve
> > > > > tried it again 3 times with same result. Rayilyn
> > > > >
> > > >
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