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Hi Bob, I was able to work for 10 years following my diagnosis. By that time Sinemet was no longer working as well as it had in the past so I was started on permax. But everyone is affected differently with this disease. I have now had PD for 25 years carol gray ---------------------------------------------------------------------- To sign-off Parkinsn send a message to: mailto:[log in to unmask] In the body of the message put: signoff parkinsn